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Fastise 200 is an antibiotic with bactericidal effect, indicated in cases of bacterial, parasitic, and fungal infections. So what are the uses of Fastise 200 and what should be noted when taking the drug?
1. What is Fastise 200?
Fastise 200 has the main ingredient is Cefbuten - the 3rd generation Cephalosporin antibiotic in the beta lactam group. Like other Cephalosporin antibiotics, Fastise 200 has a bactericidal effect through the mechanism of inhibiting bacterial cell wall synthesis, thereby lysis of pathogenic bacteria.
Fastise 200 has a broad antibacterial spectrum, can be effective against most strains of Gram-positive (Streptococcus pneumoniae, Streptococcus pyogenes,...) and Gram-negative (Haemophilus, Haemophilus influenzae, Moraxella, E.coli, Shigella) , Salmonella,...) .
Fastise 200 is rapidly absorbed from the gastrointestinal tract. Immediately after oral administration, the drug binds to plasma proteins about 65% and enters the body's organs. The drug is eliminated mostly in the urine.
2. Indications of Fastise 200
Fastise 200 is indicated for the treatment of infections caused by susceptible bacteria:
Respiratory tract infections: Acute exacerbation of chronic bronchitis, pneumonia, acute bronchitis. Acute sinusitis, pharyngitis, tonsillitis . Acute otitis media. Urinary tract infections.
3. Contraindications of Fastise 200
Do not use Fastise 200 for patients who are allergic to Cefbuten, cephalosporin antibiotics or any of its ingredients.
Some notes when using Fastise 200 :
Patients who are allergic to penicillin are at risk of being allergic to Fastise 200 . In patients, long-term use of broad-spectrum antibiotics may increase resistance in susceptible strains of resistant bacteria. Patients with renal impairment using Fastise 200 need to reduce the dose. Children under 6 months of age should not take the drug. There are no studies to prove the safety of the drug in children and nursing women. Therefore, it should be considered before taking the drug.
4. Some possible interactions of Fastise 200
Some possible interactions of Fastise 200 include:
Tobacco, alcohol, alcoholic drinks or fermented foods can change the composition of the drug. High doses of aluminum hydroxide/magne hydroxide antacids, ranitidine and single dose intravenous theophylline : did not significantly alter the effects of Fastise 200. The potency of the drug was unchanged by food.
5. Dosage and how to use Fastise 200
Fastise 200 is made in the form of tablets that should be taken orally. The patient should swallow the tablet whole, do not crush, do not chew the medicine. Accordingly, taking during or after meals does not affect drug metabolism.
Dosage
Adults and children over 12 years old: Initial dose is 400mg x 1 time / day, taken for 7-10 days. Children from 6 months to 12 years old: The starting dose is 9 mg/kg x 1 time/day, orally for 7-10 days. The maximum dose used is 400mg/day. Patients with renal failure with a glomerular filtration rate of 30-49ml/min: orally 4.5mg/kg/day or 1 tablet of Fastise 200mg/day. Patients with renal failure with glomerular filtration rate from 5-29ml/min: take 2.25mg/kg/day or take 1/2 tablet of Fastise 100mg/day. Patients on peritoneal dialysis: 9 mg/kg or 2 Fastise 200 mg tablets at the end of each dialysis session.
6. Side effects of the drug Fastise
When using Fastise, you may experience some unwanted side effects as follows:
Erythema, erythema multiforme. Allergic reaction. Pseudomembranous colitis. Nausea, vomiting. Jaundice. Leukopenia, thrombocytopenia. Thus, Fastise is a broad-spectrum antibiotic, sensitive to many strains of Gram-negative and Gram-positive bacteria. Drugs are indicated in many pathological cases, but patients need to use the drug according to the instructions, do not arbitrarily change the dose, stop the drug or use the drug for a long time, which will cause drug resistance.
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