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Fasthan 20 drug is a drug that works in the treatment of lipid metabolism disorders, helping to reduce cholesterol, triglycerides, LDL-cho. To learn more about the uses and notes when using the drug, please refer to the article below.
1. Uses of Fasthan 20
Fasthan 20 drug has the main ingredient is Pravastatin sodium 20mg, belongs to the group of statin drugs, the drug works to treat dyslipidemia and prevent cardiovascular events. Pravastatin is a competitive inhibitor of hydroxymethylglutaryl coenzyme (HMG-CoA) reductase, thereby preventing the conversion of HMG - CoA to mevalonic acid, which is a precursor of cholesterol. Therefore, Pravastatin sodium has the effect of inhibiting cholesterol biosynthesis, reducing cholesterol in liver cells. In addition, it also helps to increase the appearance of LDL-cholesterol receptors on the surface of liver cells, thereby increasing LDL clearance. This active ingredient helps to reduce VDLD-c, Triglyceride, increase HDL-cholesterol (good blood fat).
It is applied in clinical with the effect of lowering plasma cholesterol, treating dyslipidemia, anti-atherosclerosis and preventing primary and secondary cardiovascular events.
2. Indications and contraindications when using Fasthan 20
Indication of Fasthan 20 drug in the following cases:
Treatment of dyslipidemia: Treatment of primary hypercholesterolemia and mixed dyslipidemia if non-pharmacological measures are not effective. Patients need to combine maintenance with a healthy diet. Prevention of primary cardiovascular events: Helps to reduce mortality and cardiovascular morbidity in patients with moderate to severe hypercholesterolemia, in combination with dietary modification. Secondary myocardial infarction prevention: Reduce mortality from cardiovascular events and reduce recurrence in people with a history of myocardial infarction, unstable angina, which may be associated with increased or no increase in blood cholesterol. Reducing blood lipids in people who have received organ transplants and are taking anti-rejection drugs. Contraindications of Fasthan 20:
There is a history of hypersensitivity to any ingredient of the drug. People with liver disease, liver enzyme test index is abnormally high. Pregnant women and lactating women.
3. Usage and dosage of Fasthan 20
How to use: The drug is taken orally, the patient should take the drug with water, it can be taken with or without food.
Dosage: You can refer to the manufacturer's dosage as follows:
Adults
Treatment of dyslipidemia: Take a dose of 10 - 40mg/time/day. Maximum 40mg/day. Depending on the response to adjust the dose accordingly. Prevention of primary and secondary cardiovascular events: 40mg once daily. For both the starting dose and the maintenance dose. Reducing blood lipids in transplant patients who are taking anti-rejection drugs: Starting dose 20mg/time/day. Then, depending on the response, the doctor will adjust the dose to suit each patient. Maximum dose 40mg/day. Children from 8 to 13 years old: Use dose 10 - 20 mg/time/day. Children from 14 to 18 years old: Use 10-40mg/time/day. Elderly people: Drink as directed by your doctor. Patients with moderate and severe hepatic and renal impairment: The starting dose is about 10mg/time/day.
4. Undesirable effects when using Fasthan 20
The drug can cause some side effects when used as follows:
Unexplained muscle pain, pain often occurs in a persistent way; muscle aches or cramps. When these symptoms appear, the patient should stop taking the drug and notify the doctor immediately. Especially patients with symptoms of fever, cold, fatigue. In some cases, taking the drug can lead to rhabdomyolysis, severe kidney failure, and life-threatening. Allergic reactions can cause: swelling of the face, lips, tongue, difficulty breathing. When having these signs, the patient should immediately notify the doctor and move to the nearest medical facility. Double vision, blurred vision, dizziness, fatigue, headache, sleep disturbance, insomnia. Gastrointestinal disturbances such as dyspepsia, nausea and vomiting, abdominal pain, diarrhea, and constipation may occur. Itching, boils, urticaria, hair loss, painful urination, nocturia. In rarer cases, symptoms such as: Itching, heat, numbness due to nerve damage, skin manifestations such as lupus erythematosus may occur. Hepatitis, pancreatitis, causing jaundice, hepatocellular necrosis. Myositis leads to weakness, muscle pain, tendinitis can lead to tendon rupture. Memory loss, confusion, etc. may also occur. Tests may show elevated liver enzymes.
Patients should inform the doctor of any side effects encountered during use.
5. Notes when using Fasthan 20
Before taking the medicine you need to inform your doctor about any history of allergy to the drug or to anything before. Medical history, especially liver disease, because it has a risk of causing elevated liver enzymes.
The medicine is taken once a day, so it is rare to forget the medicine. However, if you forget, you should take the dose as soon as possible, if it is almost time for your next dose, skip the missed dose, do not double the dose at the next dose.
Drugs can cause interactions when used with other drugs. Therefore, patients should be aware of drugs that may interact as follows:
Fibrates, gemfibrozil, high-dose niacin, colchicine: When used together may increase the risk of unwanted effects on muscle, such as rhabdomyolysis. Therefore, these drugs should not be used together unless absolutely necessary and under close monitoring. Cholestyramine and colestipol: Concomitant administration of the drug may reduce the bioavailability of pravastatin by 40-50%. Therefore, patients can take Fasthan 1 hour before or 4 hours after Cholestyramine/colestipol. Immunosuppressive drugs such as cyclosporin may increase the bioavailability of Fasthan when used concurrently. Macrolide antibiotics such as erythromycin, clarithromycin should be used with caution. Medicines for HIV and hepatitis C such as darunavir, ritonavir, lopinavir, ritonavir increase the risk of muscle damage, rhabdomyolysis and kidney failure. In addition, during the use of the drug, the patient should not drink alcohol, because both alcohol and this drug are harmful to the liver.
For people who have to operate machinery, the drug usually has no effect. However, if you have side effects such as dizziness, blurred vision, double vision, you should not drive or operate machinery.
When taking the drug, you still need to follow a diet to control blood fat, exercise regularly to maintain a reasonable weight.
Usually there are no special symptoms with an overdose of pravastatin and the patient can recover quickly. However, if you accidentally overdose, you need to notify your doctor for timely examination and monitoring. The medicine should be stored in a dry place, away from direct light, the storage temperature is below 30 degrees Celsius. It is necessary to keep the medicine out of the reach of small children.
Fasthan 20 drug when used shows high treatment efficiency, but it can still cause some unwanted side effects. Therefore, you should not self-medicate, but need to use it under the prescription of a doctor.
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