Emanera contains the main active ingredient Esomeprazole, which is effective in reducing acid secretion in the stomach. The absorption of Emanera 40mg is not affected by food, so patients can take it before or after meals.
1. What is Emanera 40mg?
Emanera 40mg is an antacid. Each Emanera 40mg tablet contains the following ingredients:
The main active ingredient is Esomeprazole with a content of 40mg;
Excipients just enough for the tablet.
2. Effects and indications for use of Emanera 40mg
Effects of Emanera 40mg:
The active ingredient Esomeprazole has the activity of inhibiting the gastric proton pump. In the acid compartment of the parietal cell, the active ingredient Esomeprazole will be protonated and converted into active achiral sulfenamide. Thereby inhibiting its activity and the parietal cell secretes H + ions into the stomach.
In addition, the active ingredient Esomeprazole is also an inhibitor of gastric acid secretion, so it is effective in gastroesophageal reflux disease, indigestion, gastric and duodenal ulcers and Zollinger-Ellison syndrome.
With the above effects, Emanera 40mg is indicated in the following cases:
Treatment of esophageal ulcers caused by gastric reflux;
Prevention of recurrent esophagitis;
Treatment of symptoms of gastroesophageal reflux.
Combining Emanera with antibiotics in the eradication of Helicobacter pylori bacteria.
Treatment and prevention of gastric-duodenal ulcers caused by NSAID use.
Emanera 40mg is also used in the treatment of Zollinger-Ellison syndrome and cases of increased gastric acid secretion.
Used for long-term treatment after intravenous treatment to prevent rebleeding of gastric-duodenal ulcers.
In addition, there are some other effects of the drug that are not listed on the approved label but your doctor may prescribe you to use. What you should do is follow your doctor's instructions.
3. How to use and dose Emanera 40mg?
3.1. Dosage of Emanera 40mg
Treatment of symptoms of gastroesophageal reflux:
- Support treatment of reflux esophagitis: Take 40mg of Emanera daily for 4 weeks. If the patient still has inflammation, consider using it for another 4 weeks.
- Prevention of the risk of recurrence of esophagitis: The daily dose of Emanera is 20mg.
- Gastroesophageal reflux disease: For patients without reflux esophagitis, take 20mg daily.
- Combined with other antibiotics to kill Helicobacter pylori bacteria: Take 20mg in combination with 1g Amoxicillin and 500mg Clarithromycin, twice daily for 7 days.
Dosage of Emanera 40mg for patients taking NSAIDs:
Prevention of gastric ulcers caused by NSAIDs: Take 20mg daily. Use for 4 to 8 weeks.
Prevention of gastric ulcers in people at risk of gastric-duodenal complications but need to continue using non-steroidal anti-inflammatory drugs: Take 20mg daily.
Treatment of Zollinger-Ellison syndrome:
The initial dose of Emanera is 40mg, taken twice daily. Then, depending on the patient's response to the drug, adjust the dose accordingly.
3.2. How to use Emanera 40mg?
The absorption of Emanera 40mg is not affected by food, so patients can take it before or after meals. Take the medicine with a little water, do not bite or chew the tablet.
4. Side effects of Emanera 40mg
When using Emanera 40mg, you may experience some of the following unwanted effects:
- Common: Headache, abdominal pain, constipation, diarrhea, bloating, nausea
or vomiting; - Uncommon: Metabolic and nutritional disorders such as peripheral edema, insomnia, dizziness, paresthesia, drowsiness, dry mouth, increased liver enzymes, itching or rash on the skin, more dangerous is bone fracture;
- Rare: Leukopenia and thrombocytopenia, fever, angioedema, anaphylactic shock, hyponatremia, agitation, confusion, depression, taste disturbance, blurred vision, dizziness, bronchospasm, gastrointestinal candidiasis, hepatitis with or without jaundice, severe hair loss and photosensitivity, joint and muscle pain, interstitial nephritis, personality changes, increased sweating;
- Very rare: Blood and lymphatic system disorders (leukopenia, pancytopenia); metabolic and nutritional disorders (hypomagnesemia); hepatobiliary disorders (encephalopathy in patients with pre-existing liver disease, liver failure); skin and subcutaneous tissue disorders (toxic epidermal necrolysis, erythema multiforme, Stevens-Johnson syndrome); other side effects such as irritability, hallucinations, muscle weakness, gynecomastia or microscopic colitis.
The above are not all the side effects of Emanera. If you experience any other side effects, you should stop using the drug and notify your doctor or go to the nearest medical facility for appropriate treatment.
5. Drug interactions
When Emanera 40mg is used at the same time with antibiotics such as Clarithromycin or Penicillin, it can increase the concentration of Esomeprazole and antibiotics in the blood, easily causing a dangerous overdose for the patient's health.
When Emanera 40mg is used at the same time with Diazepam, it can reduce the clearance of Diazepam by 45%, increase toxicity and cause symptoms of drug poisoning.
When Emanera 40mg is used in combination with Atazanavir, it will reduce the concentration of Atazanavir. Therefore, these two drugs should not be used together.
6. Notes on using and storing Emanera
Before using Emanera 40mg, you need to read the instructions carefully and refer to the information below.
Emanera 40mg is not indicated in the following cases:
- People who are sensitive to the active ingredient Esomeprazole, the Benzimidazoles group or any ingredient of the drug;
- Patients with rare genetic problems such as fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase deficiency should not use Esomeprazole.
7. Caution when using Emanera 40mg
When unusual symptoms such as significant unintentional weight loss, vomiting (with or without blood), difficulty swallowing, black stools appear, it is necessary to rule out malignancy because treatment with Emanera can reduce symptoms and delay diagnosis;
For patients who have to be treated with Emanera 40mg for a long time, regular monitoring is needed;
When symptoms change in characteristics, patients should contact their doctor;
Treatment with proton pump inhibitors can increase the risk of gastrointestinal infections caused by Salmonella and Campylobacter strains;
Emanera 40mg can reduce vitamin B12 absorption. Therefore, it is necessary to consider using the drug in people with reduced vitamin B12 reserves or at risk of reduced vitamin B12 absorption during long-term treatment;
Patients at risk of osteoporosis should be cared for according to clinical guidelines, supplemented with appropriate amounts of vitamin D and calcium.
Above is information about the uses, dosage and how to use Emanera 40mg. All information in the article is for reference only, the use of the drug must follow the instructions of a medical specialist to ensure health safety.
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