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Drug Diamicron MR 60mg is made in the form of tablets, with the main ingredient is Gliclazide. It is used to treat type 2 diabetes, in combination with proper nutrition and exercise.
1. Uses of the drug Diamicron MR 60mg
What is Diamicron MR 60mg? Gliclazide is a sulphonylurea, a urea derivative, used orally to lower blood sugar. Gliclazide lowers blood glucose levels by stimulating insulin secretion from the beta cells of the islets of langerhans. Increased postprandial insulin and C peptide secretion persisted after 2 years of treatment. Along with this metabolic property, Gliclazide also has hemato-vascular effects.
Drug Diamicron MR 60mg is indicated in the following cases:
Reduce blood sugar level; Treatment of type 2 diabetes in adults (when diet, exercise, and weight loss fail to keep blood sugar at an appropriate level). The drug Diamicron MR 60mg is contraindicated in the following cases:
People with hypersensitivity to Gliclazide or its components, other drugs of the sulfonylurea group or to hypoglycemic sulfonamides; People with type 1 diabetes; People with diabetic ketoacidosis, pre-coma or diabetic coma; People with severe liver or kidney disease; People who are taking the antifungal medicine Miconazole; Mother is breastfeeding.
2. How to use and dose Diamicron MR 60mg
2.1. How to take Diamicron MR 60mg is used orally. Patients should take half of the tablet (the pill can be broken into two equal halves) or the whole tablet whole, without chewing or breaking the tablet. Tablets should be taken with 1 glass of water in the morning (preferably at the same time each day). After taking the medicine, it is necessary to eat well.
2.2. Dosage The usual dose is 1⁄2 - 2 tablets (maximum dose 120mg) in 1 pill at breakfast. Dosage can be changed depending on the response to treatment and factors such as weight loss, stress, lifestyle,... If it is necessary to combine Diamicron with other drugs, the doctor will prescribe the appropriate dose for the patient. patient. If your blood sugar remains high despite taking your medication as prescribed, you should notify your doctor.
If you take an overdose of Diamicron, the patient should tell the doctor or go to the nearest hospital. Overdose symptoms can be relieved by eating 4-6 pieces of sugar or drinking sugar water immediately, followed by other foods. If the patient is unconscious, call an ambulance and notify the doctor immediately. The above temporary emergency measures are also taken if anyone else has taken Diamicron by mistake. If the patient is unconscious, do not give the patient anything to eat or drink.
If the patient forgets to take Diamicron MR 60mg, the patient should take the next dose at the usual time. In particular, patients need to pay attention to taking medicine every day because regular treatment will have better effects.
3. Side effects of the drug Diamicron MR 60mg
When using Diamicron MR 60mg, patients may experience some side effects such as:
Hypoglycemia: The most common side effect. If left untreated, symptoms can progress to drowsiness, loss of consciousness, coma, etc. If a severe or prolonged episode of hypoglycemia occurs, even when blood glucose is under control. temporarily by eating sugar, the patient still needs to go to the doctor right away; Liver disorders: Taking Diamicron can cause jaundice, yellow eyes. This symptom usually disappears when the drug is stopped. When experiencing the above symptoms, you should notify your doctor to consider whether to stop treatment or not; Skin disorders: There are cases of using Diamicron with rash, redness, itching of the skin, angioedema (swelling of the eyelids, face, lips, tongue, mouth, throat, which may cause difficulty breathing). The rash may progress to diffuse blistering or peeling; Blood disorders: There are cases when taking Diamicron medicine, the number of blood cells (white blood cells, platelets, red blood cells) is reduced, causing pale skin, prolonged bleeding, sore throat, fever, and bruises on the skin. These symptoms usually resolve when the drug is stopped; Gastrointestinal disorders: Nausea, vomiting, dyspepsia, abdominal pain, diarrhea or constipation. These symptoms will be reduced if Diamicron is taken with meals; Eye disorders: The patient's vision may be affected for a short time, especially when Diamicron is started; Other side effects: Severe changes in blood cell counts, allergic inflammation of blood vessel walls, symptoms of impaired liver function (jaundice), hyponatremia,... In most of these cases, Symptoms disappear when the drug is stopped. However, in some isolated cases, patients can experience life-threatening liver failure. If you experience unwanted effects when using Diamicron MR 60mg, the patient should immediately notify the doctor.
4. Be careful when using Diamicron MR 60mg
Some issues patients need to keep in mind before and while taking Diamicron:
Follow your doctor's treatment plan to achieve an appropriate blood sugar level. Thus, in addition to using the drug regularly, the patient should adhere to the diet, exercise and lose weight if necessary; While taking Diamicron, it is necessary to regularly monitor blood sugar, urine sugar and HbA1C index; During the first weeks of treatment with Diamicron, the risk of hypoglycaemia may be increased and the patient should be closely monitored; Hypoglycemia can occur in the following cases: Irregular intervals between meals or skipping meals; Diet; Malnutrition; change the diet; increased exercise but not adequate carbohydrate intake; drinking alcohol, especially associated with skipping meals; taking Diamicron with other medicines; taking the drug Diamicron in too high a dose; have specific hormone-related disorders (function of the thyroid gland, pituitary gland, adrenal cortex); severe impairment of liver or kidney function. Symptoms of hypoglycemia include: Headache, hunger pangs, nausea, vomiting, fatigue, restlessness, sleep disturbances, poor concentration, decreased alertness, depression, confusion, visual disturbances, speech disorder, tremor, dizziness,...; Patients may experience the following symptoms after taking Diamicron: Sweating, moist skin, fast or irregular heartbeat, anxiety, increased pain, sharp and sudden pain in the chest, which may radiate to the surrounding area. . If blood glucose levels continue to drop, the person may experience delirium, convulsions, loss of control, shallow breathing, slow heart rate, and loss of consciousness. When you have low blood sugar, you should use glucose tablets, sugar tablets, ...; Symptoms of hypoglycaemia may not be obvious or appear very slowly if the patient taking Diamicron is elderly and is being combined with certain other drugs (beta-blockers, central nervous system drugs). ,...); If the patient is in a stressful period (surgery, fever, accident,...), the doctor may temporarily switch the patient to insulin; Symptoms of hyperglycemia can occur when Gliclazide does not decrease as much as expected, the patient does not follow the doctor's regimen, or is under extreme stress. Symptoms include: Thirst, dry mouth, dry itchy skin, increased urination, skin infections, decreased activity,...; If you have a personal or family history of G6PD deficiency, which can cause low hemoglobin and broken red blood cells, consult your doctor before taking Diamicron; Do not use Diamicron MR 60mg for children; If you have low blood sugar or high blood sugar, you experience visual complications, your ability to concentrate and react may be impaired. You should consult your doctor if you can drive or operate machinery if you have frequent low blood sugar or have no warning signs before hypoglycemia; Do not take Diamicron MR 60mg during pregnancy and lactation.
5. Drug Interactions Diamicron MR 60mg
Drug interactions can affect the effectiveness of Diamicron and other drugs and increase the side effects of some drugs. Therefore, patients should inform the doctor about the drugs they are using for advice and appropriate regimen adjustment.
The hypoglycemic effect of Gliclazide (a component of Diamicron) may be enhanced, signs of hypoglycemia may occur when used in combination with the following drugs:
Other drugs used to treat hyperglycemia blood sugar (insulin, GLP receptor agonist, other oral antidiabetic); Antibiotics (clarithromycin, sulfonamide); Medicines for high blood pressure or heart failure (angiotensin-converting enzyme inhibitors or beta-blockers); antifungal medicine (fluconazole, miconazole); Drugs for gastric and duodenal ulcers (H2 receptor antagonists); Medicines for depression (monoamine oxidase inhibitors); Painkillers, anti-rheumatic drugs (ibuprofen, phenylbutazone); The drug contains alcohol. The hypoglycaemic effect of Gliclazide (a component of Diamicron) may be reduced, signs of hyperglycemia may occur when used in combination with the following drugs:
Drugs for central nervous system disorders ( chlorpromazine); Anti-inflammatory drugs (corticosteroids); Medicines for asthma or during labor (intravenous salbutamol, terbutaline and ritodrine) Medicines for breast disorders, heavy menstrual bleeding, endometriosis (danazol). In addition, Diamicron Mr 60mg may increase the effect of anticoagulants (such as warfarin).
Also, do not take Diamicron with food and alcoholic beverages. Patients on medication should also not drink alcohol because it will alter blood sugar control.
When using Diamicron Mr 60mg, patients should inform their doctor about their health status, allergy history and medications they are using. If you experience any side effects or unusual reactions, you should tell your doctor right away.
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