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Devasco 5 is a drug, is it a drug to treat high blood pressure? With the main ingredient being Benazepril, Devasco 5 is a drug used alone or in combination in the treatment of hypertension and congestive heart failure.
1. What is Devasco 5?
Devasco 5 belongs to the group of cardiovascular drugs, with the main ingredient being Benazepril hydrochloride 5mg. Benazepril is an angiotensin-converting enzyme inhibitor and reduces peripheral arterial resistance.Devasco 5 is made in the form of film-coated tablets and is indicated for use in the following cases:
Treatment of hypertension (alone or in combination with thiazide diuretics). Treatment of congestive heart failure (used in combination with Digitalis and diuretics) in case the patient does not respond to other treatments.
2. Usage and dosage of Devasco 5
Devasco 5 is taken orally, taking it with water. Note, before using Devasco 5, patients need to stop diuretics for 2-3 days, except in cases of uncontrolled hypertension or rapid and malignant increase in blood pressure.
Dosage of Devasco 5 in the treatment of specific hypertension is as follows:
Initial dose: 10mg/time/day. For patients with dehydration and sodium loss due to past or current use of diuretics, patients with renal impairment (creatinine clearance less than 30 ml/min), an initial dose of 5 mg should be used and monitored for at least 2 hours. after taking medication to prevent excessive hypotension. Maintenance dose: 20-40mg/day, can be used once/day or divided into 2 times a day. Dosage of Devasco 5 in the treatment of congestive heart failure is as follows:
Initial dose: 5mg/time/day. Maintenance dose: 5-10mg/time/day. For patients with renal insufficiency, it is necessary to lower the dose of Devasco 5 or extend the time between doses.
The effect of the drug is achieved when dosing once a day. However, within 24 hours after taking the drug, if there is evidence of hypotension, it is necessary to divide the total daily dose into 2 to use.
3. Devasco 5 . side effects
Devasco 5 can cause some unwanted side effects, but most are mild and temporary. Age, duration of treatment or dose (in the range of 2 - 80mg) did not affect the side effects of the drug.
The frequency of occurrence of side effects of Devasco 5 is as follows:
Common: Cough, dizziness, headache, somnolence, fatigue, nausea. Uncommon: Tachycardia, hypotension, angioedema, insomnia, anxiety, agitation, erythema multiforme, Stevens - Johnson syndrome, photosensitivity skin, hyperkalemia, thrombocytopenia, leukopenia, vomiting, constipation, gastritis, black stools. Devasco 5 rarely causes jaundice, urinary tract infections, impotence, muscle pain/weakness, pain/arthritis, paresthesia, hypertonia, sinusitis, bronchitis, asthma, dyspnea, sweating . Unspecified: Agranulocytosis, common in people with kidney failure or damaged blood vessels (due to lupus erythematosus or scleroderma). If you see any strange symptoms after taking Devasco 5, the patient should immediately notify the treating doctor or go to a medical facility for a health examination.
4. Some notes when using Devasco 5
Do not use Devasco 5 in people with hypersensitivity to the drug's components or angiotensin converting enzyme inhibitors. In pregnant women, especially in the second and third trimesters of pregnancy, taking Devasco 5 may increase the incidence or mortality of infants due to amniotic fluid deficiency, hypotension or neonatal oligohydramnios. urinary/anuria. Therefore, pregnant women should not take this medicine. If used together with Devasco 5 with diuretics, in the beginning may cause excessive hypotension. Concomitant use of Devasco 5 with antihypertensive drugs may cause severe hypotension; with non-steroidal anti-inflammatory drugs may antagonize the antihypertensive effect; with sympathomimetic drugs may reduce the antihypertensive effect. Concomitant use of Devasco 5 with potassium-sparing diuretics or potassium supplements may increase blood potassium levels; Use with Lithium may increase serum Lithium concentrations and lead to toxicity. In summary, the use of Devasco 5 is to reduce blood pressure (alone or in combination with diuretics) and peripheral resistance in people with congestive heart failure (used in combination with diuretics and Digitalis). To ensure safety for health and maximize the effectiveness of treatment, patients need to take Devasco 5 exactly as directed by their doctor.
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