This is an automatically translated article.
Captussin New Tablets are a combination of 2 anti-inflammatory effects of Betamethasone and H1 antihistamine Dexlorpheniramine maleate. The combination of Betamethasone and Dexchlorpheniramine maleate allows to reduce the dose of Corticosteroids while still providing the same effect when using Corticosteroids alone with higher doses.
1. What is Captussin New?
Captussin New drug is made in the form of capsules, packing in plastic bottles of 100 tablets.
The main ingredients of the drug Captussin New include:
Betamethasone (0.25mg); Dexchlorpheniramine maleate (2mg); Excipients have sufficient drug content. The oral bioavailability of the active ingredient Dexchlorpheniramine maleate is close to 82%. Peak plasma concentrations are reached 1-2 hours after dosing. Dexchlorpheniramine maleate is bound to proteins at a concentration of about 90-95%. The clearance of Dexchlorpheniramine maleate is 8.7 ± 1.6 ml/min/kg. The volume of distribution of Dexchlorpheniramine maleate is 1.5 ± 0.2 liters/kg. Dexchlorpheniramine maleate is metabolised in the liver, the half-life of this active substance is approximately 1.7 - 2.7 hours.
2. Indications for taking Captussin New
Captussin New drug is indicated in the following cases:
Treatment of complicated cases of respiratory, skin and eye allergies; Treatment of inflammatory eye disease requires indicated support with systemic corticosteroids. Treatment of allergic conjunctivitis, keratitis, choroiditis, chorioretinitis, non-granulomatous blepharitis, iridocyclitis.
3. Dosage, how to use Captussin New drug
The dose of Captussin New should be adjusted according to the severity and response of the patient. As disease progresses, the dose of Captussin New should be reduced to the minimum maintenance level and discontinued as soon as possible.
Dosage of Captussin New refer to the following:
Adults and children over 12 years old: Start with 1-2 tablets / time x 4 times / day. Do not exceed 8 Captussin New tablets/day. Children from 6 to 12 years old: The recommended dose of Captussin New is 1/2 tablet x 3 times/day. If necessary, the dose of Captussin New can be increased but should not exceed 4 tablets/day. How to use the drug:
Take Captussin New after eating and before going to bed; Take the medicine exactly as directed by your doctor. In case of forgetting or overdose of Captussin New, it is necessary to consult a doctor for appropriate treatment. The above dose of Captussin New is for reference only. The specific dose of Captussin New will depend on the condition and the progression of the disease. To get the right dose of Captussin New, patients need to consult their doctor or pharmacist.
4. Contraindications to taking Captussin New
Captussin New drug is contraindicated in the following cases:
People with hypersensitivity to any component of Captussin New or drugs with similar structure; People with systemic fungal infections, viral infections or taking MAOIs. Infants and preterm infants; Contraindicated in pregnant women.
5. Interactions with other drugs
Concurrent use of Captussin New with Phenobarbital, Phenytoin, Rifampicin or Ephedrin may increase the metabolism of corticosteroids, reduce the therapeutic effect of the disease; Corticosteroids should be monitored for excessive effects if Captussin New is used concomitantly with estrogens; Captussin New used with potassium-depleting diuretics may cause hypokalemia; Concomitant use with cardiac glycosides may increase cardiotoxicity and effects with hypokalemia; Captussin New may also increase the potential for potassium loss when used concomitantly with Amphotericin B; Increase or decrease the anticoagulant effect when using Captussin New with Coumarin type anticoagulant; Increased severity of peptic ulcers when used with alcohol and non-steroidal anti-inflammatory drugs; Reducing the concentration of salicylic in the blood when combining Captussin New with Acetylsalicylic acid; Monoamine oxidase (MAO) inhibitors increase the effects of Captussin New, causing severe hypotension; Concomitant use with alcohol, tricyclo barbiturates or central nervous system depressants may increase the effect of Captussin New; The effect of anticoagulants can be inhibited by Captussin New.
6. Captussin New drug side effects
Captussin New drug may cause some of the following side effects:
Water and electrolyte disturbances, congestive heart failure; High blood pressure; Muscle weakness, osteoporosis, aseptic necrosis of the ends of bones; Peptic ulcer can cause perforation and gastrointestinal bleeding, pancreatitis; Slow wound healing; Skin dystrophy; Hemorrhagic spots; Menstrual disorders; Cushing's syndrome; Posterior subcapsular cataract; Glaucoma,... To prevent dangerous side effects, during the course of treatment, if there are any abnormal symptoms suspected of using Captussin New, the patient should notify the doctor. treatment for timely treatment.
7. Be careful when using Captussin New drug
For Betamethasone:
Caution should be used when betamethasone is used in people with nonspecific ulcerative colitis, active or latent peptic ulcer, abscess or other pyogenic infection, inflammation diverticulum, anastomosis, renal failure, high blood pressure, osteoporosis and severe myasthenia gravis; Prolonged use of Betamethasone can lead to posterior subcapsular cataracts, optic nerve damage, and secondary fungal or viral eye infections; Moderate and high doses of Betamethasone may increase blood pressure, salt/water retention, and potassium excretion. Therefore, patients need to establish a diet that limits salt and provides extra potassium. Dexchlorpheniramine maleate:
Should be used with caution in patients with narrow-angle glaucoma, peptic ulcer, pyloric obstruction/bladder neck, prostate enlargement, hypertension, increased intraocular pressure or hyperthyroidism ; Antihistamines often cause dizziness, sedation and hypotension in the elderly, so they should be used with caution in patients over 60 years of age; The drug can affect the ability to use machines and drive, so it should be used with caution in these subjects. In summary, Captussin New drug is useful in the treatment of complex cases of allergies of the respiratory tract, skin and eyes. Captussin New can cause side effects that affect the patient's health, so it is necessary to use the drug exactly as prescribed by the doctor / pharmacist.
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