This is an automatically translated article.
The article was written by Pharmacist Nguyen Huy Khiem - Faculty of Pharmacy - Vinmec Times City International General HospitalChlorpheniramine is an antihistamine used quite commonly for allergic conditions (including allergic rhinitis, urticaria, contact dermatitis, food allergies, allergic conjunctivitis, ...). This is a drug used without a doctor's prescription, but in order to achieve good and safe treatment effects, patients when using Chlorpheniramine can note some of the information below.
1. Why drugs have anti-allergic effects?
Allergic symptoms (including: itching, urticaria, swelling of the lips, eyes,...) are usually due to the release and effect of histamine when it binds to receptors in the body. . Chlorpheniramine works by blocking the allergenic effects of histamine by preventing histamine from binding to H1 receptors in tissues in the gastrointestinal tract, vascular wall, and respiratory tract.
In addition, the drug has the ability to penetrate into the central nervous system, inhibiting the effect of acetylcholine, thus also exhibiting sedative effects, reducing body fluid secretion (saliva, tears,...)
Do Accordingly, Chlorpheniramine is classified as a first-generation (non-selective) H1 antihistamine.
Chlorpheniramin là một thuốc kháng histamin được dùng khá phổ biến cho các tình trạng dị ứng
2. Dosage
Adults and children > 12 years old: 4mg/time; Dose may be repeated every 4-6 hours if needed, do not exceed 24 mg/day. Children 6-12 years old: 2mg/time; Dose may be repeated every 4-6 hours if needed, not exceeding 12 mg/day. Children 2 - 6 years old: 1mg/time; Dose may be repeated every 4-6 hours if necessary, not exceeding 6 mg/day. Do not use for children < 2 years old.
Thuốc không sử dụng cho trẻ em dưới 2 tuổi
3. Care should be taken when using Chlorpheniramine for which patients?
The drug has a sedative effect, causing drowsiness, so care should be taken when using it for people who are driving or operating machinery. The drug can cause urinary retention, caution when used for prostate enlargement. Not giving priority to the elderly > 65 years old because this patient is more susceptible to unwanted effects of the drug: cognitive impairment, dry mouth, constipation,... Lactating women: drugs Passes breast milk, and may cause a decrease in breast milk production
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