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Atelec Tablets belongs to the group of cardiovascular drugs, used to lower blood pressure in people with high blood pressure. The active ingredient Cilnidipine in the drug helps to inhibit calcium ions from entering the blood vessel walls, reducing vasoconstriction, reducing blood pumping pressure at the heart.
1. What is Atelec Tablets?
Atelec Tablets is a specialized drug for the group of cardiovascular diseases, namely symptomatic treatment of hypertension. The drug is produced and packaged in blister form, one blister includes 10 film-coated tablets, each box has 10 blisters.
Atelec Tablets, also known as Atelec Tablets 10, is made up of the main active ingredient, Cilnidipine 10 mg, and other excipients. The antihypertensive effect of Cilnidipine is demonstrated by its strong affinity for dihydropyridine, which binds to this receptor and inhibits calcium ion causing vasoconstriction.
2. What are the effects of Atelec Tablets?
Atelec Tablets have the active ingredient Cilnidipine. This active substance antagonizes calcium, thereby demonstrating the ability to vasodilate, reduce blood pressure and lower blood pressure.
The mechanism of action of Cilnidipine is explained as follows:
As soon as it enters the body, Cilnidipine will be metabolized into the blood. The high affinity of the drug causes Cilnidipine to form a bond with dihydropyridine, which then obstructs and inhibits the flow of Ca2 positive ions through the smooth muscle of blood vessels, causing vasodilation and reduction of vessel wall pressure.
Cilnidipine's inhibitory effect on calcium channels in the sympathetic nerve cell membrane also reduces the secretion of norepinephrine at the sympathetic nerve endings. This drug also inhibits the rapid reflex contraction of the heart, thanks to its sympathomimetic activity during and after lowering blood pressure, inhibiting hypertension.
Atelec Tablets is indicated for use in the following cases:
Indications for the use of Atelec in patients with primary hypertension
3. Usage of Atelec Tablets
3.1. How to use Atelec Tablets Atelec Tablets are absorbed from the gastrointestinal tract, so patients can swallow Atelec Tablets whole with an appropriate amount of liquid, such as filtered water. Patients should avoid crushing or breaking the drug to arbitrarily divide doses, take whole tablets to maximize the pharmacodynamic and pharmacokinetic properties of release.
Take Atelec after breakfast, take it once a day.
3.2. Dosage of Atelec Tablets The recommended dose of Atelec Tablets is as follows:
For adults with hypertension: The recommended dose for this population is from 5 to 10 mg each time, taken once in a day. day. Depending on the age and symptoms of the patient, the doctor will make specific dose adjustments. The maximum dose that can be used for adults is 20 mg once daily.
For people with severe high blood pressure: The recommended dose for this person is 10 to 20 mg each time. Do not take more until symptoms have not improved.
3.3. If you miss a dose of Atelec Tablets, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take as directed by your doctor. Patients should not take two doses at the same time, to avoid causing overdose. Overdose: When a patient takes an overdose of Atelec Tablets, symptoms of severe hypotension may occur. At this time, treatment measures can be carried out by placing the patient in a lying position, lifting the lower extremities to help reverse blood flow, using drugs to increase blood pressure and giving fluids to balance electrolytes and hypernatremia. . Hemodialysis and hemodialysis do not remove Cilnidipine due to its high affinity, protein binding 3.4. Atelec Tablets Contraindications Do not use Atelec Tablets in patients with a history of hypersensitivity to Cilnidipine or a hypersensitivity reaction to any other ingredient of Atelec Tablets. Do not use Atelec Tablets for pregnant women, suspect the possibility of pregnancy and lactation
4. Precautions when using Atelec Tablets
Side effects of Atelec Tablets
When using Atelec Tablets, patients may experience unwanted side effects as follows:
Liver dysfunction: Increased AST, ALT or LDH Renal dysfunction: There is a risk of urinary sediment, increased creatinine or ururia Cardiovascular problems: The patient may experience flushing, palpitations, and a drop in blood pressure. Gastrointestinal disorders: Patients may experience nausea, abdominal pain to vomiting Drug Interactions Atelec Tablets
Do not use Atelec Tablets with other antihypertensive drugs at the same time because it may cause blood pressure to be too low. Calcium antagonists such as Atelec Tablets used with Digoxin increase blood levels of Digoxin. Co-administration of Atelec Tablets with Cimetidine enhances the effect of calcium channel blockade. The reason for this is that Cimetidine reduces the volume of blood through the liver, thereby preventing the metabolism of Cilnidipine in the liver. The cytochrome P 450 metabolic enzyme will be more active in the presence of Rigampicin, thereby reducing the effect of Cilnidipine when used concurrently. Drinking grapefruit juice during treatment increases blood Amol levels. Store Atelec Tablets
Store Atelec Tablets 10 mg in a dry place, away from sunlight Keep Atelec at room temperature, below 30 degrees Celsius Store Atelec Tablets in sealed packaging Atelec Tablets is a prescription medicine , used to treat hypertension through calcium antagonists. Use of the drug requires the direction and prescription of a doctor.
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