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Asiclacin 500 is manufactured and registered by Sao Kim Pharmaceutical Joint Stock Company. So what is Asiclacin 500 used for? how to use? Let's find out more through the article below.
1. What is Asiclacin 500?
Asiclacin 500 medicine has the main ingredient containing the active ingredient Azithromycin dihydrate with a concentration of 500mg, made in the form of film-coated tablets, packing in a box of 1 blister of 3 tablets.
2. The effect of the drug Asiclacin 500
Mechanism of action of Asiclacin 500:
Active ingredient Azithromycin is a bacteriostatic antibiotic belonging to the Macrolide group. The drug inhibits protein synthesis of bacterial cells by binding to the 50S ribosomal subunit, preventing the translocation of peptidyl-RNAt from the acceptor site to the donor site, so the new aminoacyl-RNAs do not can bind to the receptor site, so the amino acids cannot attach to the existing peptide chain.
Asiclacin 500 is indicated for use in the following cases:
Indicated in the treatment of infections caused by susceptible bacteria such as lower respiratory tract infections (pneumonia, bronchitis, otitis media). ; soft tissue and skin infections; upper respiratory tract infections (pharyngitis, sinusitis, tonsillitis). Because of the risk of drug resistance, Asiclacin 500 should only be used in patients who are allergic to penicillin group antibiotics. Asiclacin 500 is also used to treat uncomplicated genital infections caused by Neisseria gonorrhoeae or Chlamydia trachomatis without multidrug resistance.
3. How to use and dose Asiclacin 500
3.1. How to take Asiclacin 500 Asiclacin 500 is produced in the form of tablets, used orally, patients should take the drug about 1 hour before a meal or 2 hours after eating. Use 1 time a day.
3.2. Dosage of Asiclacin 500 In adults:
In the treatment of sexually transmitted diseases such as urethritis, cervicitis caused by Chlamydia trachomatis infection: use a single dose of 1g. In the treatment of pneumonia, bronchitis, pharyngitis, soft tissue and skin infections: The initial dose is 500mg/time, extended for 4 days with a single dose of 250mg/day. In children:
The starting dose should be used with a concentration of 10mg/kg body weight, from day 2 to 5, using a dose of 5mg/kg body weight/x 1 time/day.
4. Undesirable effects of Asiclacin 500
During the use of Asiclacin 500, besides the therapeutic effects of the drug, the patient may experience undesirable effects such as:
Nausea, vomiting, loss of appetite, lack of energy; Dizziness, headache, fainting, excessive fatigue; hives, itching, rash, unusual bleeding or bruising; Wheezing/difficulty breathing or swallowing; fast heartbeat, yellowing of the skin or eyes, dark urine; Diarrhea, abdominal pain; Hoarseness, swelling of face/throat/tongue/lips/eyes/hands/legs/ankles or shins; mouth sores, severe diarrhea (bloody or bloody stools) with or without fever; Pain in the upper right part of the stomach; Stomach pain may persist for more than 2 months after stopping the drug; Skin blistering or peeling; Flu-like symptoms, unusual muscle weakness or difficulty controlling muscles. Patients are advised to report any unusual symptoms immediately to their doctor for instructions on timely handling and effective supportive treatment.
5. Asiclacin 500 . drug interactions
Bioavailability of the drug can be reduced by up to 50% when taken with food. Therefore, it is necessary to use Asiclacin 500 medicine away from meals. Do not use together ergot derivatives with Asiclacin 500 because of the potential for toxicity. The use of Asiclacin 500 should be avoided with antacids, it should be used 1 hour before or after 2 hours. The metabolism of Cyclosporin can be interfered with by some macrolide antibiotics, so it is necessary to monitor and adjust the dose of Cyclosporin accordingly. Asiclacin 500 can significantly affect the metabolism of Digoxin in the intestine, so during the simultaneous use of these two drugs, it is necessary to monitor the concentration of Digoxin.
6. Note when using Asiclacin 500
Contraindications of Asiclacin 500:
Asiclacin 500 is not contraindicated in patients with hypersensitivity to Azithromycin, antibiotics of the Macrolide group and any of the excipients in the drug. Precautions when using Asiclacin 500:
May encounter allergic reactions such as angioedema and anaphylaxis which are very dangerous, although rare, but should be used with caution when appointing Asiclacin 500 and other antibiotics. belonging to another group of Macrolides. In pregnant women and lactating mothers, there are no reports or research data, so do not use for these subjects. Use only in the absence of other suitable medications and under the direction of a physician. Do not use Asiclacin 500 for subjects with liver disease because the drug is mainly eliminated by the liver.
7. Preservation of Asiclacin 500
Store Asiclacin 500 in a cool, dry place, avoid direct sunlight or high temperature because it can change the ingredients in the medicine. Suitable storage temperature is from 25 to 30 degrees Celsius. Keep out of reach of children, keep medicine in sealed container.
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