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Mahacillin Sachet is an antibiotic that is prepared in the form of an oral mixture. The drug is useful in the treatment of certain infectious diseases. To better understand the use of Mahacillin Sachet, please read and follow the content in the following sharing!
Mahacillin Sachet is manufactured by Akums Drugs and Pharmaceuticals Ltd. Each pack of Mahacillin Sachet 3g contains: Ampicillin (in the form of Ampicillin trihydrate) 250mg with excipients including: Anhydrous silica 12.0 mg, sodium methyl hydroxybenzoate 3.0 mg, aspartame 6.0 mg, sodium propyl hydroxybenzoate 0.75 mg, sugar glass 2635.56 mg and dry vanilla flavor 21.0 mg.
1. Indications and uses of medicine Mahacillin Sachet
Mahacillin Sachet medicine contains Ampicillin - a broad-spectrum penicillin antibiotic, patients can only use it according to prescriptions and prescriptions of specialists. The drug is used in the treatment of a number of infectious pathological conditions as follows:
Inflammation of the upper respiratory tract and lower respiratory tract; Soft tissue infections, gastrointestinal tract, urinary tract, ENT; Meningitis , gonorrhea, blood infection, typhoid; Bacterial endocarditis, peritoneal infection;
2. Dosage - How to take Mahacillin Sachet
2.1 How to take Mahacillin sachet Medicine is put into the patient's body through oral route.
2.2 Dosage of Mahacillin sachet Adults:
Patients with ENT infections: Mahacillin sachet 250mg/time x 4 times/day. Patients with bronchitis: Normal dose: 250mg/time x 4 times/day. High dose: 1 gram/time x 4 times/day. Pneumonia patients: Mahacillin sachet 500mg/time x 4 times/day. Patients with urinary tract infections: Mahacillin sachet 500mg/time x 3 times/day. Patients with gastrointestinal infections: 500 to 750mg/time x 3 to 4 times/day. Patients with Typhoid: Acute 1 to 2 grams/time x 4 times/day in the first 2 weeks. In case of people carrying bacteria: 1 to 2 grams / time x 4 times / day for a period of 4 to 12 weeks. Patients with Gonorrhea: 2 grams of Mahacillin sachet + 1 gram of Probenecid as a single dose. Repeated doses are recommended when treating gonorrhea in women. Elderly:
The therapeutic dose is the same as that of adults, but the dose may be reduced in some subjects with impaired renal function. Children (children under 10 years old):
Use Mahacillin sachet 1⁄2 doses compared to the adult dose. Note: Dosage needs to be prescribed by the treating doctor. In some severe infections, the dose may be increased or ampicillin used parenterally. Patients should take the drug 30 minutes to 1 hour before meals.
Patients with renal impairment:
For severe renal failure (creatinine clearance less than 10 ml/min) it is necessary to reduce the dose or prolong the treatment time between doses. For patients with renal failure undergoing hemodialysis, an additional dose should be used after hemodialysis.
3. Contraindications of the drug Mahacillin Sachet
Contraindicated to use Mahacillin Sachet for:
There is a history of hypersensitivity to antibiotics: Penicillin, Ampicillin and some Cephalosporin antibiotics. Hypersensitivity to any other excipients. Have diabetes.
4. Interactive Mahacillin Sachet
Consumption of food may decrease the absorption of Ampicillin. Ampicillin interacts with drugs: probenecid, allopurinol. Ampicillin is incompatible with Aminosides, tetracyclines and the antibiotics amphotericin, metronidazole, clindamycin phosphate, erythromycin lactobiona, lincomycin hydrochloride and polymyxin B sulfate. Ampicillin is inactivated by: Acetylcysteine, chlorpromazine hydrochloride, dopamine hydrochloride, heparin calcium or sodium, hydralazine hydrochloride, hydrocortisone sucinate, metoclopramide, prochlorperazin edisylate, procloperazine mesylate eg sodium bicarbonate.
5. Side effects of Mahacillin Sachet
Common: Diarrhea, rash (exanthema). Uncommon: Thrombocytopenia, anemia, leukopenia, agranulocytosis and eosinophilia. Glossitis, stomatitis, pseudomembranous colitis, colitis and urticaria. Rare: Anaphylactic reactions and exfoliative dermatitis, erythema multiforme. Interstitial nephritis, increased AST. Patients should inform their doctor about any side effects when using Mahacillin Sachet.
6. Overdose and treatment
When using an overdose of Mahacillin Sachet, patients may experience symptoms such as nausea, vomiting, diarrhea.
Treatment Instructions: Remove Ampicillin from the systemic circulation by hemodialysis.
7. Precautions when using Mahacillin Sachet
Renal failure, neonates, premature infants: reduce dose. Keep medicine out of reach of children. Do not use the medicine past the expiry date printed on the package. Mahacillin Sachet should not be used or used with caution in patients with hypersensitivity to Cephalosporins. It is necessary to check the functioning of the liver, kidneys and blood when the patient has a treatment duration of more than 2 - 3 weeks. Minimize the use of Mahacillin Sachet with patients infected with Epstein-Barr virus and HIV virus because of possible erythema.
Pregnancy and breast-feeding: Mahacillin Sachet does not harm an unborn baby. In nursing women, Ampicillin is not expected to cause adverse reactions in nursing infants at normal therapeutic doses in breast milk. The above is important information about the uses of Mahacillin Sachet. To ensure the effectiveness of Ampicillin, the drug needs to be stored at a temperature below 30 degrees Celsius and protected from light and moisture.
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