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Articudar drug containing the active ingredient Diacerein is indicated in the treatment of osteoarthritis, degenerative joint disease and related disease symptoms,... Let's learn about the uses, notes when using Articudar through the article below. .1. Uses of Articudar
1.1. Uses of the active ingredient Diacerein
Active ingredient Diacerein acts by inhibiting the production and activity of Interleukin-1, which is a pro-catabolic and pro-inflammatory substance in both the superficial and deep layers of cartilage, the synovial fluid and in the synovial membrane. In addition, Diacerein also stimulates the production of transforming growth factors, stimulating components of the extracellular matrix such as aggrecan, proteoglycan, hyaluronic acid and type II collagen. Diacerein also inhibits phagocytosis and migration of macrophages. Studies in several animal models of osteoarthritis have shown that Diacerein reduces cartilage degeneration compared with animals not treated with Diacerein.Studies have also shown significant pain relief and improved joint function when taken with placebo after about one month of treatment with Diacerein, beneficial effects may persist for up to 2 months after treatment by medicine.
1.2. Indications for the drug Articudar
"What does articudar do?" Articudar medicine contains the active ingredient Diacerein 25mg in the form of hard capsules and is indicated in the treatment of osteoarthritis, degenerative joint disease and related disease symptoms.2. Dosage of Articudar
Articudar belongs to the group of prescription drugs, the dose of which is prescribed by the treating doctor. Patients should absolutely not self-administer the drug without the prescription of the treating doctor.Some recommendations on the dose and administration of Articudar are as follows:
Articudar should be taken with the main meal to help increase absorption; The average dose in adults is 2 tablets/time x 2 times/day; For patients with renal failure, the dose should be reduced by half.
3. Articudar side effects
Articudar can cause some of the following undesirable effects:Common: Abdominal pain and decreased time for food to pass,... These symptoms are common in the first few days of taking the drug and will subside when Continued treatment Darkens urine. In case of experiencing unwanted side effects, the patient should stop using the drug and notify the doctor for examination.
4. Notes when using Articudar
Articudar is contraindicated in patients with hypersensitivity to Diacerein, anthraquinone derivatives or any of its ingredients. Do not use Articudar in pregnant or lactating women. In patients with renal impairment, it is important to reduce the dose based on creatinine clearance. Use caution when using Articudar in patients who drive or operate machinery.5. Drug interactions
Articudar can interact with laxatives, so do not use these two drugs at the same time.Possible drug interactions that reduce the therapeutic effect of Articular, increase the risk of unwanted effects. Therefore, to ensure safety and effectiveness, patients need to inform their doctor about the drugs and functional foods they are using before being treated with Articudar 25mg.
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