What is Menison 4mg?

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1. What is Menison 4mg?

Menison 4mg has the main active ingredient methylprednisolone, a glucocorticoid that is a 6-alpha-methyl derivative from prednisolone with anti-inflammatory, immunosuppressive and anti-allergic properties. forward.
The mechanism of action of Menison is to increase the production of neutrophils, and at the same time reduce the number of lymphocytes, monocytes, eosinophils... present in the blood and in the periphery. Thanks to this action, the function of lymphocytes and macrophages is inhibited, and the response to antigens and mitogens is also suppressed. This is how the drug Menison suppresses the immune system.
For its anti-inflammatory effect, Mension works by reducing prostaglandin synthesis and limiting capillary permeability by inhibiting kinin activity, bacterial endotoxins and reducing histamine present in basophils.
The composition of one Menison 4mg tablet (in addition to Methylprednisolone) each tablet also contains other excipients such as lactose, microcrystalline cellulose, hydroxypropyl cellulose, sodium starch glycolate, talc and magnesium stearate.

2. What are the effects of Menison 4mg?

The effects of Menison 4mg have been demonstrated through many drug indications in nonspecific therapies but require anti-inflammatory - immunosuppressive capabilities. Therefore, Menison 4mg is very often present in therapies for the treatment of problems related to osteoarthritis, post-traumatic inflammation, acute gouty arthritis... In addition, the drug is also used to Treatment of vasculitis, nodular arteritis and temporal arteritis.
In addition to the anti-inflammatory effect, Menison 4mg also has many benefits in other issues such as:
Indication Menison 4mg in the treatment of bronchial asthma, especially acute asthma attacks. Treatment of problems related to allergic reactions such as allergic rhinitis, drug sensitivities/hypersensitivity, anaphylactic activity, etc. Immune diseases such as lupus erythematosus or acute rheumatic heart disease. Primary nephrotic syndrome, thyroiditis, adrenal insufficiency (both primary and secondary), hypercalcemia in cancer patients... For cancer, Menison 4mg is also used for acute leukemia, breast cancer, lymphoma and prostate cancer. Blood-related diseases such as leukopenia or hemolytic anemia are also often used Menison 4mg in treatment.

3. Dosage of menison 4mg

Initial dose of Menison 4mg 1 to 12 tablets per day (equivalent to 4mg to 48mg per day). This initial dose will be maintained and gradually increased until a response is obtained. In case the patient needs to use Menison for a long time, the dose should start with the lowest dose to which the body responds well to the drug, then gradually reduce until the signs/symptoms of the disease. increased again, increase the dose of the drug.
It is also important to note that, even if the disease is no longer symptomatic, you still have to use the drug but at a lower dose until it is completely stopped. Never stop taking it suddenly, especially if you have been using Menison 4mg for a long time.
Menison 4mg dose is specifically indicated depending on the pathology as well as the health status and age of the patient, in which, some common indications are:
Indication of Menison drug for acute asthma: Dose Usually used is 8 to 12 tablets per day (corresponding to 32 to 48mg) and used continuously for 5 days. After this time, you should reduce the dose gradually over the next 1 week, until the acute attack has ended, reduce the dose at a faster rate until the drug is completely stopped. For rheumatoid arthritis, Menison 4mg is maintained from 1 to 1.5 tablets per day. In some cases, a higher dose of 4 to 8 tablets per day can be used, then gradually reducing the dose until the drug is completely stopped. For low-grade diseases, the initial dose of Menison 4mg is 0.8mg per kg of body weight per day and divided into several small doses. In children, with severe complications of chronic arthritis, Menison 4mg should be started at an initial loading dose of 10 to 30mg per kg body weight, with approximately 3 sessions per day. Menison in acute and chronic ulcerative colitis will maintain from 8mg to 24mg per day, corresponding to 2 to 6 tablets depending on the doctor's prescription. Primary nephrotic syndrome will use Menison 4mg at a dose of 0.6 to 1.6mg per kg of body weight daily for the first 6 weeks continuously, then will start to gradually reduce the dose over the next 6 to 8 weeks. For immune-related hemolytic anemia, Menison 4mg dose is 16 tablets daily and taken continuously for the first 3 days, then reduce the dose as prescribed by the doctor for the next 6-8 weeks.

4. Notes and cautions when using Menison 4mg

First of all, Menison 4mg or drugs containing methylprednisolone are generally contraindicated in cases such as:
Just vaccinated with live attenuated virus. Patients with dermatological lesions associated with fungi, viruses or active tuberculosis. In addition, it is necessary to be more careful when prescribing Menison 4mg to groups of subjects with osteoporosis, stomach ulcers, diabetes, high blood pressure, children in puberty...
Menison 4mg medicine also has some unwanted effects when used for a long time with too high dosage, especially some serious side effects are:
Increased ability and extent infection of the body due to the immunosuppressive mechanism of the drug. May increase blood pressure, increase the risk of stomach ulcers, bleeding or even stomach perforation. Causes the skin to atrophy, less elastic and prone to acne. Weakened muscles and slower growth... In general, Menison 4mg has many effects in the treatment of immune and anti-inflammatory diseases. However, long-term use of the drug will leave negative consequences. Therefore, you should only use it exactly as prescribed by your doctor.

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