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Anadrol is used in the treatment of acquired or congenital aplastic anemia, anemia caused by decreased red blood cell production. Find out more about the uses and precautions when using the drug through the article below.1. Uses of the drug Anadrol
Anadrol medicine has the active ingredient oxymetholone. Available in tablet form, Anadrol 50 contains the equivalent of 50mg of oxymetholone.
Anadrol 50 (Oxymetholone) is a synthetic derivative of testosterone. Oxymetholone has been shown to enhance the production and secretion of erythropoietin (a hormone involved in erythropoiesis) in patients with anemia due to bone marrow failure and to stimulate erythropoiesis in patients with anemia due to red blood cell deficiency.
When taking this medicine can cause some harmful reactions such as causing serious growth and sex development disorders if used in young children. They block the gonadal functions of the pituitary gland and can directly affect the testes.
2. Indications and contraindications for taking Anadrol
Indications for use of Anadrol in the following cases:
Indicated in the treatment of anemia caused by a lack of red blood cell production. Acquired aplastic anemia, congenital aplastic anemia, myelofibrosis. Hypoplastic anemias caused by administration of myelotoxic drugs also often respond. Note that the use of drugs should not replace other supportive measures such as blood transfusion, correction of iron deficiency, folic acid, vitamin B12 or pyridoxine, treatment with antibacterial drugs...
Contraindicated in drug use in the following cases:
Carcinoma of the prostate or breast in a male patient. Breast carcinoma in women with drug-induced hypercalcemia may stimulate bone resorption. Oxymetholone can harm an unborn baby when administered to a pregnant woman. Therefore, it is contraindicated in women who are or may become pregnant. If the patient becomes pregnant while taking the drug, the doctor should be informed of the possible risk to the fetus. Kidney failure or nephritis. Hypersensitivity to any of the ingredients contained in the drug. Severe liver dysfunction.
3. Administration and dosage of Anadrol
Anadrol is to be taken with water. The tablet should be swallowed whole with water, do not chew or crush the tablet to avoid breaking the drug's structure.
Dosage:
The recommended daily dose in children and adults is 1-5 mg/kg body weight per day. The usual effective dose is 1-2 mg/kg/day, but sometimes higher doses may be required. Duration of medication: It should be taken for a minimum of three to six months. After remission, some patients can be maintained without medication; Others may be maintained at a lower daily dose at the loading dose.
4. What side effects may be encountered when taking Androl
Besides the effects, the drug can cause unwanted effects. Some undesirable effects that may be encountered when taking the drug include:
Liver damage: Cholestatic jaundice, rarely liver necrosis and death. Hepatocellular tumors and pelvic hepatis have been reported in association with long-term use of the drug. Men: Enlarges the volume and increases the frequency of erections. If the age after puberty, the drug can inhibit testicular function, testicular atrophy, hypoplasia, impotence, chronic narrowing of the foreskin, epididymitis, bladder irritation and hypovolemia. For women: Enlarged clitoris, irregular menstruation. For both sexes: Increased or possibly decreased libido. Side effects on the Central Nervous System: Excitement, insomnia. Gastrointestinal: Nausea and vomiting, diarrhea. Hematology: Bleeding in patients receiving concomitant anticoagulant therapy, iron deficiency anemia. Leukemia has been observed in patients with aplastic anemia treated with oxymetholone. However, the role of oxymetholone is not really clear because malignant transformation has been seen in patients with blood dysfunction and leukemia has been reported in patients with untreated aplastic anemia. treated with oxymetholone. Tumors of the mammary glands, making the female voice deeper. Hair loss and male pattern baldness in girls, male pattern hair loss after puberty. Acne (especially common in women and boys before puberty). Causes early ossification, muscle spasms, chills. Causing edema, retaining electrolytes in serum such as sodium, chloride, potassium, phosphate... Decreased glucose tolerance, increased serum low density lipoprotein concentration and decreased high density lipoprotein concentration, increased excretion creatine and creatinine, increased serum creatinine phosphokinase (CPK) levels. Reversible changes in liver function tests such as increased serum bilirubin, glutamic-oxaloacetic transaminase (SGOT) and alkaline phosphatase. You should tell your doctor right away if you experience any side effects while taking this medicine and if you have any other problems.
5. Some notes when taking Anadrol
Before taking the medicine, tell your doctor about your medical history and allergy history. To ensure the safest medication prescription. As drug administration may increase the risk of serious liver disease, liver tumors have also been reported, and an increased risk of developing prostatic hypertrophy and prostatic carcinoma in elderly patients. It is necessary to monitor and visit periodically to detect abnormalities early. Because of the potential for hepatotoxicity and many serious liver conditions that can be life-threatening, routine blood tests are needed to detect abnormalities early. In patients with cardiovascular disease, drugs that increase LDL-cholesterol are associated with an increased risk of atherosclerosis and coronary artery disease. Women taking the drug should be observed for signs of virilization (lower voice, hirsutism, acne and clitoral growth). To prevent this change from being irreversible, drug therapy must be discontinued for monitoring. Some cases have been reported where this condition could not be reversed even with discontinuation of the drug. Periodic radiographs (every 6 months) should be performed when treating prepubertal patients to determine the rate of bone maturation and the effect of therapy on the child's body. It is not known whether the drug affects a nursing infant. Therefore, do not breast-feed while taking the drug. Drug interactions may occur with drugs such as Warfarin, other anticoagulants... in addition, taking the drug may interact with other drugs. You should talk to your doctor so he can give you the best advice. Store the medicine in a cool place, out of direct sunlight and out of the reach of children. Hopefully, the above information has helped you understand the uses and things to keep in mind when using Anadrol. If you have any questions, you should consult your doctor directly.
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Reference source: drugs.com
