This is an automatically translated article.
Dexamethasone is an active ingredient in the Corticosteroid group with strong anti-inflammatory intensity. This active ingredient is in the drug Alphamethasone DHT with a concentration of 0.5mg. So what are the indications of Alphamethasone 0.5mg and what problems should be noted when using?
1. What is Alphamethasone-DHT?
Alphamethason DHT is a product of Ha Tay Pharmaceutical Joint Stock Company, prepared in tablet form with packing specifications of 20 blisters each, corresponding to each blister of 30 tablets.
Ingredients Alphamethasone 0.5mg contains the active ingredient Dexamethasone with the corresponding concentration and some other excipients just enough in 1 tablet.
2. Effects of Alphamethasone DHT
The active ingredient Dexamethasone in Alphamethasone DHT has the following effects:
This active ingredient is essentially a synthetic Glucocorticoid, capable of binding to receptors in cells with the exact location in the nucleus. After binding, Dexamethasone affects a number of translated genes; Active ingredient Dexamethasone Alphamethasone 0.5mg has strong anti-inflammatory effects, besides the ability to fight allergies and suppress the immune system; The anti-inflammatory effect of Dexamethasone is 30 times stronger than Hydrocortisone and Prednisolone 7 times. With the above effects, Alphamethasone DHT is indicated for the following cases:
Inhibits inflammation in many diseases such as rheumatoid arthritis, systemic lupus erythematosus, acute gout, dermatological diseases (such as rheumatoid arthritis, systemic lupus erythematosus, acute gout). psoriasis, drug dermatitis, atopic dermatitis, contact dermatitis ), ulcerative colitis, Crohn's disease and bronchial asthma; Alphamethason 0.5mg is used to treat dermatitis caused by Herpes virus, impetigo, severe psoriasis, severe seborrheic dermatitis, Eczema...; Some chronic inflammatory and allergic diseases in parts of the eye such as uvea, conjunctiva, iris, optic nerve; Alphamethasone DHT is also used to treat some other diseases such as blood cell cancer, idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia, thyroiditis, lymphoma, sarcoid disease; Or used in hormone replacement therapy in adrenal insufficiency.
3. Instructions for using Alphamethasone 0.5mg
Patients need to carefully read the detailed information in the Alphamethasone user manual, especially note how to use, the dose to get the best treatment effect and limit side effects.
How to use Alphamethason:
Patients need to drink whole tablets of Alphamethason 0.5mg with enough water; Never take more than the dose prescribed by your doctor. Dosage of Dexamethasone should be according to the specific prescription of the doctor, in addition to the patient can refer to the following dose:
Adults: 0.75-9mg/day (equivalent to 1.5 to 18 Alphamethasone 0.5mg tablets) divided into 2- 4 times drink. The exact dose depends on many factors such as the patient's condition and ability to respond; Children: 0.024-0.34 mg/kg/day or 0.66-10 mg/m2 skin/day, divided into 4 oral doses. How to handle missed dose:
Patients need to take the replacement dose of Alphamethasone as soon as they remember. If it is almost time for your next dose, skip the missed dose and do not take a double dose to make up for it. Alphamethasone overdose and treatment:
When taking an overdose of Alphamethasone DHT, patients often have symptoms of acute poisoning, even death; Treatment: Dexamethasone overdose cases should be taken to the nearest medical facility immediately for timely monitoring and treatment. Dexamethasone poisoning does not have a specific treatment, but mostly just symptomatic treatment.
4. Contraindications of Alphamethasone DHT
The following cases are not suitable to use this Dexamethasone preparation:
Hypersensitivity to Dexamethasone or any ingredient in Alphamethasone; People with systemic fungal infections, local viral infections, tuberculosis or gonorrhea infections that have not been controlled with antibiotics; Severe joint damage.
5. Undesirable effects of Alphamethasone 0.5mg
Common side effects when using Alphamethasone DHT include:
Hypokalemia, salt and water retention causing edema and/or hypertension; Cushing's syndrome, adrenal atrophy, decreased ACTH secretion Decreased glucose tolerance; Menstrual disorders; Reversible muscle atrophy; Osteoporosis, pathological fracture, spina bifida, aseptic osteonecrosis; Peptic ulcer, gastrointestinal bleeding; Acute pancreatitis; Skin atrophy, erythema, ecchymosis; Sleepless, mentally refreshed. Some rare side effects of Alphamethasone:
Allergies or hypersensitivity, sometimes leading to anaphylaxis; Stimulates an increase in the number of leukocytes causing thrombosis; Weight gain ; Nausea, increased appetite; Sterile abscess. It should be noted that patients who are taking corticosteroids such as Alphamethasone, if the dose is reduced too quickly after prolonged treatment, may lead to withdrawal symptoms such as acute adrenal insufficiency, hypotension, relapse of the disease, even even death.
6. Drug interactions of Alphamethasone 0.5mg
Drug interactions that need attention of Alphamethasone DHT drugs when combined include:
Barbiturates, Rifabutin, Carbamazepine, Phenytoin, Rifampicin, Ephedrine, Aminoglutethimide interact to accelerate the elimination of Dexamethasone, thus possibly reducing therapeutic effect; Corticosteroids antagonize the effects of hypoglycemic drugs (including insulin), antihypertensive drugs and diuretics; Alphamethasone drugs increase the hypokalemic effect of Thiazide diuretics, loop diuretics, Acetazolamide, Carbenoxolone, Coumarin anticoagulants. To avoid drug interactions that occur during the use of Alphamethasone, patients need to inform their doctors and pharmacists about all the products they are using, along with a medical history to be closely monitored.
7. Some notes when using Alphamethasone drug
Use of Dexamethasone in pregnant women and lactating mothers:
Alphamethasone DHT has the potential to cause teratogenicity, fetal malformations in animal studies; However, in cases of preterm pregnant women, doctors may prescribe Dexamethasone at birth for the purpose of preventing neonatal respiratory failure and bronchopulmonary dysplasia; The combination of the above factors shows that the use of Alphamethasone in pregnant and lactating women should be very cautious. Effects on the ability to drive and operate machines:
Alphamethasone DHT can cause anaphylaxis, insomnia... and affect the user's ability to concentrate; Therefore, caution should be exercised when dexamethasone is used in people who drive and operate machinery. Some other special notes of Alphamethasone:
Dexamethasone and other corticosteroids can cause paroxysmal and widespread infections; Patients with bacterial meningitis are indicated to use Dexamethasone before taking other specific antibiotics; Use caution when using Alphamethasone in people with osteoporosis, recent colon surgery, psychosis, peptic ulcer, diabetes, hypertension, heart failure, kidney failure, tuberculosis...; Absolutely do not use Alphamethasone after the expiry date printed on the package. Storage conditions for Alphamethasone DHT:
Store the drug in a cool, dry place, avoiding direct sunlight; Note that Dexamethasone should be kept out of the reach of children. Alphamethasone DHT is a product of Ha Tay Pharmaceutical Joint Stock Company. The drug is effective in the treatment of inflammatory diseases in the body. To ensure effective treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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