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Anturane drug whose main ingredient is Sulfinpyrazone is often indicated in the treatment, control, prevention and improvement of gout, gouty arthritis and other syndromes. However, the use of Anturane can also bring some side effects that need to be kept in mind.
1. How does Anturane work?
Anturane drug with the main ingredient is Sulfinpyrazone with activity to increase uric acid excretion in the urine, helping to reduce blood urate levels in patients with chronic and acute gout episodes, along with promoting recurrence absorption of tophi. Therefore, Anturane is mainly indicated in 2 diseases:
Chronic gouty arthritis; Intermittent gouty arthritis. Anturane is contraindicated in patients with a history of or:
Hypersensitivity to Phenylbutazone or other Pyrazoles; Blood dysfunction; Although to date there have been no reported cases of birth defects in users of the drug, the researchers still recommend caution when using the drug in pregnant women, considering between potential risk and possible benefit. 2. How to use Anturane? Anturane is usually taken by mouth twice daily or as directed by your doctor, and can be taken with food, milk, or an antacid to relieve stomach upset. Also to prevent the risk of kidney stones, you should drink 1 full glass of water with each dose and at least 8 other glasses per day while taking the medicine.
Dosage of Anturane must be based on the patient's response to the drug, it can be used at a low dose at first and then adjusted according to uric acid levels and gout symptoms. Anturane should not be used during acute gout attacks, but should be used when the condition is stable. Note that, Sulfinpyrazone is not a pain reliever, to relieve gout pain can use prescription drugs such as Colchicine, Ibuprofen, Indomethacin...
3. Anturane side effects
The unwanted effects that may occur when using Anturane include:
Nausea, heartburn, dizziness; Lower back pain, swelling of hands, feet, feet; Difficulty urinating, pain; Change in the amount or color of urine; Easy bruising, bleeding; Passing black, tarry, bloody stools; fast or irregular heartbeat; Infection; Serious allergies. To prevent side effects when taking this medicine, patients should inform their doctor about allergic conditions to Sulfinpyrazone or Phenylbutazone, Pyrazole, bleeding, ulcers in the stomach or intestines, severe kidney disease, kidney stones. , history of bleeding due to low platelets, clotting problems, low blood volume due to anemia, acute leukemia, cancer of all kinds, diabetes, kidney disease.
4. Drug Interactions with Anturane Drug interactions that may occur when taking Anturane with other drugs include:
Cancer chemotherapy drugs, blood thinners, antithrombotic drugs (such as streptokinase); Nitrofurantoin, NSAIDs, some antiepileptic drugs; Alcohol can reduce the effectiveness of the drug; Aspirin can block the full effect of the drug, so aspirin and other salicylates should be avoided while taking Anturane. If you must take aspirin to prevent a heart attack or stroke, ask your doctor to change the dose accordingly. In summary, Anturane is often indicated in the treatment, control, prevention and improvement of gout, gouty arthritis and other syndromes. To use drugs safely and effectively, patients need to use them as prescribed by their doctor or pharmacist.
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