This is an automatically translated article.
Video content is consulted by Dr. Tran Thi Thanh Huyen - Director of Genetics Division - Vinmec Institute of Stem Cell and Gene Technology
In IVF, choosing a good embryo to prepare for embryo transfer plays a very important role. Especially in cases where there are many embryos. If the embryo is in good shape, the doctor and the couple will normally expect the embryo to have good growth potential.
However, in many studies and observations, the reality may be different, some embryos with good morphology but unsuccessful IVF results.
In every human being there is 1 set of chromosomes, the genetic set is inherited 50% from the father and 50% from the mother. Chromosome stability will determine the success of the IVF cycle. Gene tests, genetic tests to detect: Abnormal or abnormal number of chromosomes, instability in chromosome structure or abnormalities in genetic diseases can lead to abnormalities in the baby's health before performing a fresh or frozen embryo transfer.
Indications for preimplantation genetic testing should be carefully considered, divided into 2 groups: Screening tests and diagnostic tests. There should be a discussion between the clinician and the geneticist in order to determine the right type of genetic testing that is appropriate for the individual case. Families with a history of specific genetic diseases should also apply other genetic testing to supplement, to make the final decision, select embryos without chromosomal abnormalities for fresh embryo transfer or transfer of stored embryos or embryos. frozen embryo transfer.
At Vinmec, IVF Center works very closely with Vinmec Hi-tech medical genetics block to build and implement closed gene testing and genetic testing service delivery processes. Patients will receive genetic counseling before and after genetic testing, genetic testing to understand the purpose and benefits of testing as well as limitations and possible risks when preparing for embryo transfer. After that, biopsies of embryos with about 1-3,5 cells were taken for testing at Vinmec Hi-Tech Center. Genomes are cloned and sequenced at high bandwidth to provide an overview of the entire embryonic genome. Then, based on the algorithm, the software was built specifically to determine the number of chromosomes.
Gene testing has a great support for the success of the IVF cycle, helping to increase the chances of conception and the birth of a healthy baby. Statistics show that genetic testing increases the chance of IVF success by up to 60%.
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