Talazoparib: Uses, indications and precautions when using

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Talazoparib is a medication used to treat breast cancer that works by slowing or stopping the growth of cancer cells. Similar to other cancer drugs, the use of Talazoparib must be followed and strictly followed by the doctor's instructions.

1. What does Talazoparib do?

Talazoparib is a medication commonly prescribed to treat breast cancer. Talazoparib works to slow or stop the growth of malignant cancer cells.

2. How to use Talazoparib correctly?

Talazoparib is taken by mouth with or without food as directed by your doctor, usually once daily. Dosage is based on your medical condition, response to treatment, and other medications the patient may be taking.
The patient should swallow the tablet whole, avoiding breaking or dissolving the tablet. If vomiting occurs after taking a dose, the patient should not take an alternate dose immediately. Instead, take your medication on a regular schedule.
Do not increase your dose or take Talazoparib more often or for longer than prescribed. The condition of the cancer will not improve any faster, but the risk of side effects will increase.
Because Talazoparib can be absorbed through the skin and lungs and harm an unborn baby, women who are pregnant or may be pregnant should not use this medicine or come into contact with or breathe dust from the tablet.

3. Talazoparib side effects

Like many other cancer drugs, talazoparib can also cause some side effects such as nausea, vomiting, decreased appetite, diarrhea, stomach pain, abdominal pain, headache, fatigue , change in food taste or dizziness . When taking cancer drugs, many patients may experience temporary hair loss. No need to worry too much, because the hair will grow back to normal after finishing the treatment. People using talazoparib may experience some serious side effects. However, once a doctor has prescribed this medication, the benefit has been weighed against the risks of side effects. Patients should coordinate with the instructions and careful monitoring from the doctor to reduce the risk of side effects. Talazoparib reduces bone marrow function, an effect that can lead to a decrease in the number of blood cells such as white blood cells, red blood cells and platelets, thereby causing anemia, decreased ability to fight infection, easy bruising purple, bleeding. Talazoparib may also increase your risk of certain bone marrow cancers (myelodysplastic syndrome, acute myeloid leukemia). Tell your doctor right away if you have any of these symptoms: Weakness, unusual weight loss, pale skin, signs of infection (such as sore throat that won't go away, fever, chills) easy bruising, bleeding.

4. Precautions when using Talazoparib

When using Talazoparib, patients should note the following:
Before taking Talazoparib, tell your doctor if you are allergic to its ingredients or if you have any other allergic conditions. You should also tell your doctor about your medical history, especially if you have or have had kidney problems (kidney disease). Talazoparib can make people taking it easily dizzy or drowsy. Do not operate machinery, drive a vehicle, or do anything that requires alertness until you can do it safely. Talazoparib may make people taking it more susceptible to infections or may worsen any existing infections. Therefore, when using Talazoparib, you should avoid contact with people who are suffering from chickenpox, measles, flu... While taking Talazoparib, do not vaccinate without the consent of your doctor. Avoid contact with people who have recently received a live vaccine (eg, nasal flu vaccine). To reduce the risk of bruising, bleeding, or injury, use caution when using sharp objects such as nail clippers, razors, etc., and in contact and impact activities. Talazoparib is not recommended for use during pregnancy because of the potential harm to the unborn baby. Women consult their doctors about using reliable forms of contraception (such as birth control pills, diaphragms, condoms) while using the pill and for at least 7 months after stopping treatment ( 4 months for men). It is not known whether talazoparib passes into breast milk. Therefore, breast-feeding is not recommended while taking this medicine and for 1 month after stopping treatment. Women who are taking medication should consult their doctor before breast-feeding.

5. Preservation and handling in case of overdose, missed dose

If an overdose of talazoparib occurs and symptoms of unconsciousness or shortness of breath appear, the patient should be taken to the emergency room immediately. When using Talazoparib, patients are encouraged to have regular physical exams and perform medical tests such as: Analysis of the complete blood count; assessment of kidney function, pregnancy test... to check the effectiveness of drug treatment and side effects. If you forget to take a dose, skip the dose and continue taking it as scheduled. Don't take double pills to catch up. In summary, to ensure the effectiveness of treatment and limit the side effects of Talazoparib, patients should read the instructions carefully before using or as directed by the doctor. In case the use of Talazoparib is not effective, the patient should go to a medical facility for re-examination and treatment.

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Reference source: Webmd