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Latent autoimmune diabetes of adults (LADA) is a type of diabetes that is currently very little known. So what is latent autoimmune diabetes in adults?
1. What is latent autoimmune diabetes in adults?
Diabetes mellitus is a heterogeneous metabolic disorder characterized by hyperglycemia due to defects in insulin secretion, insulin action, or both. Chronic elevation of glucose for a long time causes disturbances in carbohydrate, protein, and lipid metabolism, causing damage in many different organs, especially the heart and blood vessels, kidneys, eyes, and nerves.
The most well-known classifications of diabetes today are type 1 diabetes, type 2 diabetes, and gestational diabetes. Latent autoimmune diabetes in adults (LADA) is a type of diabetes that does not have features suitable for classification.
LADA autoimmune diabetes may be referred to under a number of other names, including:
Type 2 diabetes with islet cell autoantibodies. slowly progressing type 1 diabetes (SPT1D). Type 1 diabetes of late onset. Type 1.5 diabetes. Non-insulin requiring autoimmune diabetes (NIRAD). Latent autoimmune diabetes in adults is, as the name suggests, diagnosed in adulthood. The disease has a slow onset and progression, like type 2 diabetes, but it is an autoimmune type of diabetes, so changes in diet and lifestyle do not reverse the condition.
An estimated 10% of all patients with diabetes have LADA autoimmune diabetes, and in fact the disease is very easily misdiagnosed as type 2 diabetes.
Đái tháo đường tự miễn tiềm tàng ở người trưởng thành rất dễ nhầm lẫn với đái tháo đường tuýp 2.
2. Signs suggestive of latent autoimmune diabetes in adults
Signs of the disease are similar to other types of diabetes, including:
Frequent thirst. Increased frequency of urination, especially at night. Unexplained weight loss. Blurred vision, paresthesia. However, if you are an adult with a healthy weight, an active lifestyle, and have been diagnosed with type 2 diabetes, it is likely LADA autoimmune diabetes.
In fact, without immunoassay to detect autoantibodies, but based on clinical signs and symptoms, it is very difficult to distinguish between type 2 diabetes and LADA autoimmune diabetes.
Through statistics and research, there are 5 clinical signs that people often see in the context of latent autoimmune diabetes in adults:
Age of onset is less than 50 years old. Clinical symptoms of diabetes are obvious (drinking a lot, urinating a lot, losing weight). Body mass index (BMI) < 25 kg/m2. The patient has a history of other autoimmune diseases. The patient has a family history of autoimmune disease. In the above 5 markers, if there are 2 or more markers, the patient is likely to have LADA autoimmune diabetes. Only the body mass index index has a note, that is, there are still overweight and obese patients with potential autoimmune diabetes in adults.
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3. Prevention of latent autoimmune diabetes in adults
The nature of autoimmune diabetes LADA is an autoimmune disease, so until now there is no method that can help prevent the disease. The only thing that can be done is early detection, accurate diagnosis and appropriate treatment to slow the progression of the disease and limit complications.
To register for examination and treatment at Vinmec International General Hospital, you can contact Vinmec Health System nationwide, or register online HERE.
Reference source: healthline.com
