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Tarcefandol has the main ingredient Cefamandol, which belongs to the group of antiparasitic, anti-infective, antiviral, antifungal drugs, prepared in the form of powder for solution for injection. Understanding the effects as well as complying with the indications and doses of Tarcefandol will help patients improve treatment effectiveness and prevent unwanted side effects.
1. Uses of the drug Tarcefandol
The active ingredient Cefamandol in Tarcefandol 1g is the active ingredient of the 2nd generation Cephalosporin antibiotic group. As a broad-spectrum antibiotic, the drug is capable of killing both gram-positive, gram-negative and anaerobic bacteria. Cefamandol works by inhibiting bacterial cell wall synthesis, thereby killing bacteria that are growing and dividing. Cefamandol is active against Haemophilus, gram-negative bacilli, bacteria sensitive to other cephalosporins or even some strains resistant to other cephalosporins such as indole-positive Enterobacter and Proteus species.
Cefamandol is used as a prodrug which is the ester cefamandole nafate formate, used for intravenous or intramuscular administration. Tarcefandol is used to treat respiratory tract infections, urinary tract infections, peritonitis and soft tissue skin infections caused by susceptible bacteria.
2. Indications of the drug Tarcefandol
Tarcefandol is indicated in the following cases:
Lower respiratory tract infections including pneumonia Urinary tract infections Peritonitis Sepsis Skin, soft tissue or osteoarthritis infections Prophylaxis Before and after surgery Tarcefandol should not be used in patients with a history of hypersensitivity to penicillins, cephalosporin antibiotics or any of its ingredients.
3. Dosage and how to use the drug Tarcefandol
How to use : Tarcefandol is used by intramuscular or intravenous injection. Patients must be used drugs under the manipulation and supervision of medical staff. After injection, the patient needs to rest for 30 minutes in place to monitor post-injection reactions and promptly handle any abnormalities.
Dosage:
Adults: 0.5 - 1g / time, each time 4 - 8 hours apart. In severe infections, the dose may be increased to 2g every 4 hours. The maximum dose is 12g/day Children: 50-100mg/kg/day divided into 3-6 injections depending on the child's condition. In severe infections, the dose may be increased to 150 mg/kg/day. Prophylaxis of infections caused by surgery:
30-60 minutes before surgery, 1 -2g intramuscular or intravenous injection After surgery, 1 -2g injection every 6 hours for 1-2 days. Tarcefandol must be continued until symptoms have resolved for 2 to 3 days. The minimum duration of treatment for infections caused by group A streptococcus is 10 days.
4. Tarcefandol side effects
When using Tarcefandol, patients may experience some unwanted side effects such as: Painful swelling at the injection site, abdominal pain, nausea, vomiting, diarrhea, phlebitis, Candida infection, angioedema, anaphylactic reactions, bronchospasm.
If the patient experiences the above symptoms while using Tarcefandol, it is necessary to notify the treating doctor immediately for appropriate treatment.
5. Drug interactions of Tarcefandol
Tarcefandol may interact if used concurrently with the following drugs:
Thrombolytics: increase the risk of bleeding, especially in patients with severe disease, poor nutritional status or liver disease. Aminoglycoside antibiotics: increased risk of nephrotoxicity when used concomitantly with Tarcefandol Probenecid: Decreased renal tubular secretion of Cefamandol, thereby increasing plasma drug concentrations, prolonging the duration of action and having may increase the side effects of Tarcefandol.
6. Precautions when using Tarcefandol
Use caution when using Tarcefandol for patients with renal failure, who have impaired renal function. Dosage of Tarcefandol must be adjusted based on creatinine clearance. Patients should be tested for liver and kidney function before starting Tarcefandol and should have a plan to periodically check the patient during treatment. Caution should be exercised in patients with a history of gastrointestinal disease, especially colitis. Pseudomembranous colitis has been reported in patients receiving long-term or high-dose cephalosporins. Patients should be counseled about the importance of adherence to treatment with Tarcefandol. Currently, there are no clinical reports or studies on the safety and effectiveness of Tarcefandol in pregnant or lactating women. Therefore, it must be used with extreme caution, only after weighing the benefits that outweigh the risks when using Tarcefandol for pregnant and lactating women. Should not use alcohol, beer, stimulants during treatment with Tarcefandol. There have been no reports on the effect of Tarcefandol on the ability to drive and use machines. Check the tube carefully, make sure the medicine is clear, colorless and cloudy before using it on the patient. Above is all information about the note when using Tarcefandol, patients need to carefully read the instructions for use, consult a doctor before use to achieve effectiveness and avoid unwanted effects.
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