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Antibiotics are a group of drugs used to treat diseases caused by bacteria by directly killing bacteria or slowing the growth of bacteria to help support the body's immune system to deal with the condition. this. In some serious acute infections, powerful, high-dose antibiotics are often used to save lives, but there are still some risks when using them that need to be borne in mind.
1. What are high-dose antibiotics?
High-dose antibiotics are treatments that use antibiotics in doses large enough to treat severe infections to help reduce inflammation in the patient. There are many ways to classify antibiotics, of which the common ones are divided into broad-spectrum antibiotics and narrow-spectrum antibiotics. If antibiotics work against many different types of bacteria, they are classified as broad-spectrum antibiotics, and antibiotics that work only for certain strains of bacteria are called narrow-spectrum antibiotics.
Some cases of strong antibiotic treatment can be mentioned such as:
Patients with community-acquired pneumonia have co-morbidities such as heart failure, respiratory failure, kidney failure, liver failure, diabetes or alcoholism, impaired If you are immunocompromised, fluoroquinolones (moxifloxacin 400 mg/day) in combination with a beta-lactam (amoxicillin at high dose 1 g x 3 times/day) can be used to treat patients with pulmonary abscesses or empyema on internal medicine. The department also needs to use a high dose of antibiotics from the beginning and a combination of 2 antibiotics intravenously or intramuscularly. Patients with infective endocarditis need early treatment with antibiotics with the aim of killing bacteria in the lesions. sore wound. Antibiotics with bactericidal effect, high dose and combination of 2 intravenous antibiotics for 4-6 weeks Patients with infective osteomyelitis require high-dose intravenous antibiotics, combined with antibiotics for at least a long period of time. 6 weeks
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2. The dangers of using strong antibiotics
Currently, the most common side effects of high-dose antibiotics are still nausea and diarrhea. However, in fact, using high doses of antibiotics still has many other potential risks such as:
Fungal infections: strong doses of antibiotics can change the living environment of bacteria in the body leading to fungal infections. prone to occur in some parts such as mouth, skin or under fingernails Allergic reactions: patients using high doses of antibiotics may experience allergic reactions leading to conditions such as rashes, itchy eyelids, lips swelling or even anaphylaxis. Tooth discoloration: tetracyclines are very easy to lead to tooth discoloration in children under 8 years old, while pregnant women who use this antibiotic can also give birth to babies with problems. future enamel problems Sensitization to sunlight: tetracycline, fluoroquinolone and sulfone antibiotics can directly affect the skin's sensitivity to the sun's rays causing a risk of redness or sunburn. Cardiovascular problems: A side effect of high-dose antibiotics can be cardiovascular problems that are not as common as arrhythmias or low blood pressure. Customers can go to Vinmec pharmacies in the system for advice on safe drug use.
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