What is Hapenxin 500?

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Hapenxin 500 drug has the main ingredient is Cephalexin, this is a drug indicated for the treatment of infectious diseases. To ensure effective use and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.

1. What is Hapenxin 500?


What is Hapenxin 500 drug? This medication is prescribed by doctors to effectively treat bacterial infections. Accordingly, Hapenxin 500mg is used to treat patients with respiratory tract infections, ENT, skin and skin tissue infections, urinary tract infections, and many other cases. Accordingly, the ingredients in Hapenxin 500mg also have the effect of strengthening the immune system to help attack pathogenic bacteria, thereby quickly destroying and helping patients recover quickly.
In the drug composition Hapenxin contains the main active ingredient is Cephalexin with a concentration of 500 mg and excipients sufficient.

2. In what cases is Hapenxin 500 indicated?


Thanks to the active ingredient in Hapenxin 500, the drug is indicated in the following cases:
Respiratory tract infections: Bronchiectasis with superinfection, bronchitis Otolaryngitis: otitis media, pharyngitis , sinusitis , mastoiditis, tonsillitis, streptococcal nasopharyngeal infections, Skin infections - skin structures, soft tissues and bones. Genitourinary tract inflammation: acute and chronic pyelonephritis, cystitis, acute prostatitis. People with gonorrhea and syphilis (when penicillin is not suitable). Gynecological infections Prophylaxis of urinary tract infections Prophylaxis of penicillin replacement for people with heart disease who must treat oral diseases In addition, the use of Hapenxin 500 can also be prescribed by a doctor to treat a variety of diseases. other medical conditions not listed above. Therefore, in order to have an effective prescription and use of the drug, the patient must strictly follow the instructions of the doctor.

3. In which case is Hapenxin 500 contraindicated?


Hapenxin 500 is contraindicated in the following cases:
Contraindicated to use Hapenxin 500 in patients who are sensitive to Cephalosporin and Penicillin or any of its ingredients.

4. Notes when using Hapenxin 500


During the use of Hapenxin 500, patients should pay attention to the following issues:
Cephalexin active ingredient is generally well tolerated, even in patients who are allergic to penicillin. However, there are also some very few cases of patients with cross-allergies. Long-term use of drugs containing the active ingredient cephalexin may increase the overgrowth of non-susceptible bacteria, if this is the case, the patient should stop taking the drug. There are data on pseudomembranous colitis with the use of broad-spectrum antibiotics. Therefore, attention should be paid to the diagnosis of patients with severe diarrhea during or after antibiotic use. The dose should be reduced if the patient has a history of renal impairment. Cephalexin may cause a false-positive urine glucose test with Benedict's, Fehling's solution or Clinitest tablets; In addition, it can also cause a positive Coombs test and affect the quantification of creatinine by alkaline picrate. Hapenxin 500 rarely affects the ability to drive and use machines. However, this subject still needs to be careful while using the drug. Currently, there have been no cases of Hapenxin 500 causing birth defects in the fetus. However, pregnant women should still use cephalexin only when absolutely necessary and with the advice of a doctor. The concentration of cephalexin in breast milk is quite low, but to ensure safety, the mother may consider stopping the drug while breastfeeding. In addition, prolonged use of Hapenxin can cause superinfection with resistant bacteria. Therefore, patients need to adhere to the correct dosage and instructions of the doctor, especially for patients with kidney failure.

5. Dosage and how to take Hapenxin


Hapenxin is made in the form of film-coated tablets, so it is used orally, patients should take the drug before meals to ensure effectiveness.
The patient needs to take the medicine exactly as directed by the doctor. The duration of treatment should last at least 7-10 days. Specific dosage is as follows:
In adults and children over 12 years old: 500 mg (1 tablet) x 4 times/day, depending on the degree of infection. The dose can be prescribed by the doctor up to 1 g (2 tablets) x 4 times / day (dose 4 g / day). Children from 7 to 12 years old: Take 1-2 tablets x 2 times/day. For patients with gonorrhea, a single dose of 3 g with 1 g probenecid for male patients or 2 g with 0.5 g probenecid for female patients is usually used as a single dose.
For patients with kidney disease, the dose should be adjusted as follows:
Creatinine clearance ≥50 ml/min, serum creatinine ≤132 micromol/l, the patient takes a maximum maintenance dose of 1 g, 4 times in 24 hours. Creatinine clearance 49 - 20 ml/min, serum creatinine 133 - 295 micromol/l, patients taking maximum maintenance dose of 1 g, 3 times in 24 hours. Creatinine clearance 19 - 10 ml/min, serum creatinine 296 - 470 micromol/l, patients taking maximum maintenance dose of 500 mg, 3 times in 24 hours. Creatinine clearance ≤10 ml/min, serum creatinine ≥471 micromol/l, patients taking maximum maintenance dose of 250 mg, twice in 24 hours. The dosage of Hapenxin listed above is for reference only, patients need to strictly follow the instructions for use and dosage of the consulting doctor or pharmacist.

6. How to handle an overdose of Hapenxin?


When taking an overdose of Hapenxin, patients may experience some side effects such as: Nausea, vomiting, diarrhea, seizures, especially in people with kidney failure.
The way to handle drug overdose is: protect the patient's airways, and support ventilation and intravenous fluids. In addition, the doctor may prescribe activated charcoal or gastric lavage. Accordingly, it is necessary to protect the respiratory tract for patients when handling overdose.

7. Hapenxin drug interactions


When co-administration of high-dose Cephalosporins and Aminoglycosides or together with potent diuretics may endanger renal function Probenecid may increase and prolong plasma concentrations, as well as toxicity. properties of Cephalosporins. During use, undesirable effects of Hapenxin may be encountered very rarely such as: nausea, vomiting, loss of appetite, diarrhea, abdominal pain, urticaria, dizziness, headache, fatigue ,.... Patients should inform the doctor about the unwanted effects encountered when using the drug so that they can use or change the appropriate dosage.
Hapenxin 500 drug has the main ingredient is Cephalexin, this is a drug indicated for the treatment of infectious diseases. To ensure effective use and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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