This is an automatically translated article.
The liver is the main organ, plays an important role, is like a detox factory in the body, the location of the liver is located below the right ribcage, whose main function is to provide the body with a constant source of energy. day and night, full as well as hungry.Video content is consulted by Professor, Dr. Nguyen Thanh Liem - Director of Vinmec Institute of Stem Cell and Gene Technology
In addition to activating vitamins and balancing hormones, the liver also has a chemical function of processing sugar, fat, and protein, making it easy for the body's organs to absorb.
Liver cells act as a storehouse of many important substances such as iron, vitamins, minerals... until the body needs to use them. Patients with cirrhosis have a high mortality rate only after liver cancer, which is the ultimate consequence of chronic liver disease, in which damaged cells are replaced by fibrosis, scarring and the establishment of proliferative nodules. Over time, the liver will gradually lose its ability to repair itself and function properly.
There are many causes of disease in cirrhotic patients, in which adults are susceptible to hepatitis B and C, alcoholism, and in children the main cause is biliary atrophy...
Patients with cirrhosis health will go downhill. With time, patients with cirrhosis will gradually get worse regardless of the cause. When the disease progresses to stage 4 cirrhosis (decompensated cirrhosis), most patients only have a few more years to live.
Patients with cirrhosis in the early stages of cirrhosis have very poor symptoms, even the patient has no symptoms. The patient can still work normally, there are suggestive symptoms such as: Body fatigue, difficulty urinating, slight pain in the right lower quadrant... When progressing to grade 4 cirrhosis, the patient may There are complications such as: Ascites, the patient's abdomen is getting bigger and bigger, the abdominal skin is tight because there is a lot of lemon yellow fluid in the abdomen, the blood vessels are clearly prominent on the abdominal skin above the navel and on both sides of the abdomen. The ribs, when lying down, can't see clearly, but when sitting up, the blood vessels are more prominent, the spleen is enlarged to a few centimeters below the ribs, bleeding gums, nosebleeds... Leads to liver failure, liver cancer.
Patients with cirrhosis, if not detected and treated early, will have serious consequences, blood flow from the intestines cannot return to the heart and cause gastrointestinal vasodilation, causing vomiting blood, defecation. black stools or death from blood loss. Grade 4 cirrhosis can lead to liver cancer or when toxins accumulate for a long time without using cirrhosis drugs, it may lead to hepatic coma.
Today, in addition to using drugs to treat cirrhosis, patients can use liver transplantation (grade 4 cirrhosis) which can also bring new life to patients. Recently, a new direction of modern medicine is stem cell therapy for patients with cirrhosis.
Stem cells are isolated and collected from many sources (embryo, fetus, umbilical cord blood, umbilical cord, baby teeth, from bone marrow fluid or adipose tissue of the adult body...). Stem cells after being cultured to ensure sufficient quantity to be transfused and to verify the quality requirements will be transfused into liver cirrhosis patients via hepatic vein or artery. In which the infusion of stem cells into the hepatic artery has also been shown to be safe and effective in the treatment of cirrhosis.
Vinmec Times City International General Hospital has performed a stem cell transplant to treat cirrhosis with very positive results for patients as well as opening new steps in medical progress.
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