This is an automatically translated article.
The article was professionally consulted with Specialist Doctor I Dang Thi Ngoc Chuong - Pediatrician - Pediatrics - Neonatal Department, Vinmec Central Park International General Hospital.Lung maturation injections are recommended by doctors for cases of threatened miscarriage, at risk of premature birth. Besides the benefit of reducing the risk of respiratory failure in the neonate, lung maturation injections also present some undesirable side effects.
1. Benefits of Lung Maturity Injections
There are 2 drugs that support the lungs (lung maturation drugs) that are recommended for use in cases of threatened preterm birth or at risk of premature birth from 28 to 34 weeks of age: Betamethasone and Dexamethasone (belonging to the Corticosteroid group). Recently, the use of lung maturation drugs can be extended to 26-27 weeks fetus or less than 39 weeks' gestation if elective caesarean section is required.With premature babies (born at 22 - 37 weeks gestational age), the internal organs are not functionally perfect, especially the lungs, making the baby unable to exchange air, causing respiratory failure. . Children given lung maturation injections have a reduced risk of respiratory distress syndrome, neonatal death, and other illnesses. At the same time, this therapy does not increase neonatal complications or cause intrauterine growth retardation.
Tiêm trưởng thành phổi giúp giảm nguy cơ suy hô hấp ở trẻ sinh non
2. Side effects of lung maturation injection
According to the US Food and Drug Administration (FDA), the drugs Betamethasone and Dexamethasone used for pregnant women are classified in Group C, a group that may have a risk of causing unwanted side effects.The use of lung maturation drugs may cause some adverse effects on the mother and fetus such as:
May cause negative side effects in the brain and function of the hypothalamic-pituitary-adrenal axis kidney in the fetus; Suppression of the hypothalamic-pituitary-adrenal axis in pregnant women; The drug can reduce the mother's immunity, increase the risk of fetal infection, early neonatal infection and postpartum infection in the mother; High doses of dexamethasone can cause neurotoxicity in the fetus; Causes anaphylactoid or hypersensitivity reactions, hypotension or shock-like; May cause neurodevelopmental retardation in children treated with more than 3 courses of lung maturation drugs; Maternal use of corticosteroids is associated with decreased birth weight, reduced head circumference of the child due to early ossification of cartilage and bones, early skull joint healing; After injection, lung maturation may be reduced in the fetus. However, children who receive more than 3 doses of lung maturity may develop hyperactivity disorder later in life; Lung maturation injections may cause a mild rise in blood sugar immediately after the first injection and persist for about 5 days. Therefore, pregnant women need to be screened for gestational diabetes before injection or 5 days after injection to avoid uncontrolled hyperglycemia. In general, this method is really necessary for cases with signs of threatened miscarriage or at risk of premature birth. The doctor will advise to perform lung maturation injection depending on the time and the specific actual situation to avoid having to repeat the drug, reducing the unwanted consequences for the pregnant woman and the fetus. In normal pregnancies, lung maturation injections should not be given because it may cause some effects on the pregnancy.
Note: Pregnant women should choose to have lung maturation injections at qualified medical facilities and must have constant medical supervision.
Tiêm trưởng thành phổi chỉ thực sự cần thiết cho những bà bầu có nguy cơ sinh non
The best way to take care of both mother and baby during pregnancy, start choosing a prenatal care package as soon as possible.
The Maternity Package at Vinmec International General Hospital helps customers complete antenatal check-ups and necessary tests during pregnancy, in order to minimize the risk of preterm birth. Customers registered for Maternity Package are fully cared for and checked for health of mother and baby before birth - during childbirth and after birth, fully and conscientiously.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
