This is an automatically translated article.
The article was professionally consulted by Specialist Doctor II Tran Van Trong - Specialist in Pediatric Surgery, Plastic Surgery - Aesthetics - Department of General Surgery - Vinmec Danang International Hospital.Congenital biliary atresia is a rare disease that causes obstruction of the internal, extrahepatic or entire biliary tract causing cholestatic jaundice in neonates. Congenital biliary atresia requires emergency care and early diagnosis in infancy.
1. What is congenital biliary atresia?
Congenital biliary atresia is a rare disease of the liver and biliary tract that is a disruption or deficiency of the extrahepatic biliary system, resulting in obstruction of bile flow.2. Causes of congenital biliary atresia in children
Until now, researchers have not found the exact cause of congenital biliary atresia in children, but there are many hypotheses put forward as follows: of the bile duct. Due to the occurrence of abnormalities in the embryonic period at some point during the screening process, it has not been determined that causes malformations in the biliary tract. Pregnant women are infected with viruses in the last 3 months of pregnancy such as: cytomegalovirus ( CMV), Rotavirus, Epstein-Barr Virus (EBV), HBV (hepatitis B), Rubella. Contamination of toxic chemicals or viruses causes damage to the biliary tract epithelium. According to the study, the most likely risk factors for congenital biliary atresia :Race: Asians have a higher incidence of biliary atresia in children. Gender: The disease is more common in women than in men. Family history of inherited genes. Women during pregnancy have exposure to toxins, infections, and bacterial infections.
3. Symptoms to recognize congenital biliary atresia in children
Newborns have jaundice, yellow eyes appearing 2-4 weeks after birth, accompanied by dark urine. Discolored stools: After 2-8 weeks, the baby has pale stools. This is an important symptom in the diagnosis and evaluation of the effectiveness of early surgery and subsequent follow-up. Hepatosplenomegaly: Enlarged liver due to cholestatic cirrhosis. Symptoms after a period of pathological appearance: Ascites, collateral circulation, edema,...4. Complications due to congenital biliary atresia
Children with cholangitis Bleeding in the abdominal cavity is abundant and prolonged. Obstruction of portal venous pressure. Children with liver failure. Children with poor digestion, rickets, malnutrition.5. Methods of treating congenital biliary atresia in children
Currently, to treat congenital biliary atresia in children, laparoscopic surgery to treat congenital biliary atresia in children is the new and most effective method. Children should be detected and operated early for good results. best.The best time for surgery is when the child is about 1 month old because if left for longer, the disease will turn into a late stage, so it is very important and necessary for the child to have an early examination, diagnosis and laparoscopic surgery.
Vinmec International General Hospital is one of the international general hospitals with a team of dedicated, skilled, professional, and high-tech doctors and nurses with modern equipment that can meet response is required in the treatment, laparoscopic treatment of congenital biliary atresia in children. In addition, the surgical treatment method combined with stem cells of Prof. Dr. Nguyen Thanh Liem at the Stem Cell Research Institute gives very positive results that only at Vinmec Times City, parents can rest assured. choose to take the child for examination and treatment.
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