Acute liver failure is an acute liver dysfunction that occurs within 8 weeks in children with no history of liver disease. The consequences are impaired consciousness and coagulation disorders. Prognosis depends on the cause, extent of liver damage and complications. Mortality rate is high from 20-60%.

Jaundice is a normal phenomenon in newborns. Normally, jaundice will disappear after about 1 - 2 weeks. However, many cases of children have pathological jaundice. In that case, parents need to take their children to the hospital for examination as soon as possible, to avoid dangerous complications of neonatal jaundice, affecting the child's development.

Biliary atresia is a rare disease that causes obstruction of the intrahepatic or extrahepatic bile ducts or the entire bile duct, causing cholestasis and jaundice in newborns. Biliary atresia requires emergency treatment and early diagnosis in the neonatal period.