Ingredients and uses of functional foods Fucoidan

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Article by Pharmacist Nguyen Thi Thanh Hoa - Pharmacist Pharmacy - Vinmec Times City International General Hospital

Fucoidan functional food is derived from a slime found only in brown algae. This is a functional food that supports to prevent the growth of cancer cells, inhibits blood vessel formation and supports immunity.

1. What is the ingredient in Fucoidan food?

Fucoidan is a macromolecular polysaccharides whose main component is fucose. Fucoidan is derived from a slime found only in brown algae such as Kombu, Wakame (Mekabu), Mozuku and is a water-soluble fiber, in which Mozuku seaweed has the highest Fucoidan content [1].
Okinawa Kassou Fucoidan contains 100% Fucoidan extract from Mozuku algae from Okinawa Japan combined with a proprietary molecular sieve purification technique that retains the pure Fucoidan content as high as > 95%. Each Okinawa Kassou Fucoidan capsule contains 220mg of Fucoidan concentrate.

2. What is the effect of Fucoidan food?

Functional foods Fucoidan has the effect of supporting the prevention of cancer cell growth, inhibiting angiogenesis and supporting immunity. In addition, studies also show that Fucoidan oral tablet has anticoagulant, anti-viral, antioxidant and blood lipid-lowering effects.
In cancer patients, Fucoidan supports killing cancer cells, reducing tumor size through the effects of causing cancer cells to kill themselves programmed (apoptosis), inhibiting vascular proliferation, effecting cancer cell death. decreased tumor proliferation responses.
In experimental models, fucoidan has been observed to act on a variety of exogenous and endogenous programmed death pathway triggers. Thereby inhibiting the growth and activating the process of apoptosis (programmed cell death) of cancer cells. Fucoidan inhibits the angiogenesis molecule (VEGF) from binding to receptors on the cell membrane leading to inhibiting the formation of new blood vessels of cancer cells, cutting off the supply of oxygen and nutrients to the tumor. In vivo and in vitro experiments, the angiogenic molecule VEGF was observed to be reduced in expression in the fucoidan-assigned cell group.
Fucoidan supports immunity by increasing the number and activity of NK cells (important groups of cells in the immune system) as well as increasing the number of T lymphocytes (cancer-killing cells). letters).
In single case observations in various cancers (brain tumor, thyroid cancer, breast cancer, ovarian cancer, stomach cancer...), fucoidan has been shown to be effective. Reduce tumor size, improve patient's quality of life. Fucoidan also has the effect of supporting fatigue reduction in the group of patients using chemotherapy drugs for cancer treatment.
In addition to supporting cancer patients, Fucoidan has also been observed to help reduce arthritis in patients with knee arthritis. According to the results of a randomized multicenter observational study in 2016, Martin-Martin LS et al. have shown that fucoidan-containing supplements can reduce pain and reduce the severity of knee arthritis.

3. Who should use Fucoidan food?

Okinawa Kassou Fucoidan functional food will be recommended for adults (from 18 years old) such as:
People undergoing cancer treatment, people with weakened immune systems People with signs of immunodeficiency or immune system weak epidemic (or seasonal flu ...) need to improve immune health People suffering from bone and joint diseases: arthritis, osteoarthritis ... In addition, Okinawa Kassou Fucoidan products can be used for many different subjects, not necessarily those who have the disease or are being treated for the disease

4. Note when using Japanese functional food Fucoidan

The recommended dosage of Okinawa Kassou Fucoidan food is 5 tablets/day with cooled boiled water or warm water, drink with plenty of water. In addition, users should also note:
Maintaining daily intake of Fucoidan for a period of 1-3 months will be more beneficial to health. Do not use the product for people who are sensitive to any of the ingredients of Fucoidan Kassou Okinawa. Use in pregnant women, lactating women and children is not recommended due to insufficient data on safety. Patients should inform their doctor in case you are taking other medications or supplements. The use of any food or drug can lead to side effects if not used in the right way, in the right dose. Therefore, when there is a need to use any medicine or food, you need to consult your doctor.

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REFERENCES
https://www.fucoidan-life.com/en/info_fucoidan/about_fucoidan/ Fucoidan and Cancer: A Multifunctional Molecule with Anti-Tumor Potential. (Farzaneh Atashrazm 1, Ray M. Lowenthal 1, Gregory M. Woods 1, Adele F. Holloway 2 and Joanne L. Dickinson 1 ) Randomized Observational Multicenter Study to Assess the Efficacy and Safety 0f the Association of Fortigel (10 Gr) and Fucoidan (100 Mg) in Patients with Gonarthrosis (Martin-Martin LS1*, Pierluigi B2, La Medica C3, Melis G4, Nuvoli G5, Piccinni V6, Pietrapertosa M7, Vincenti B8, Vinicola V9) Fucoidan: Structure and Bioactivity (Bo Li*, Fei Lu, Xinjun Wei and Ruixiang Zhao) Fucoidans Stimulate Immune Reaction and Suppress Cancer Growth (VACLAV VETVICKA and JANA VETVICKOVA.ANTICANCER RESEARCH 37: 6041-6046 (2017) doi:10.21873/anticanres.12051)