This is an automatically translated article.
Diagnosing diabetes in addition to determining whether the patient has the disease or not, the type of diabetes is also very important because it is directly related to the treatment plan for the patient. Therefore, autoantibody tests in the diagnosis of diabetes are necessary laboratory tests, including IAA test.
1. What is an IAA test?
The IAA test (Insulin Autoantibodies) is a test to determine anti-insulin autoantibodies in patients with type 1 diabetes or LADA diabetes. IAA testing is often the first marker to appear in children, as the disease progresses, this autoantibody disappears and the identification of anti-autoantibodies such as ICA, GADA and IA-2A is necessary. IAA testing is not common in adults. According to studies, IAA is found in 28-69% of newly diagnosed type 1 diabetes patients and in about 0.9-3% of children. Also according to these studies, anti-insulin antibodies can be present many years before the onset of type 1 diabetes. Specifically, insulin antibodies are highly sensitive, appear early, and are often the first antibodies to appear in children with type 1 diabetes.
2. Meaning of the IAA test
The IAA test is one of the autoantibody tests that aims to evaluate the classification of diabetes type as type 1 and 1.5 or type 2. If the test ICA, GADA, IA-2A is positive. ie, the presence of autoantibodies in diabetic patients, this result can diagnose type 1 diabetes. Similarly, a positive IAA test in a young patient who has not received insulin injections indicates that the patient has type 1 diabetes. type 1 diabetes.
Although there are still some cases of type 1 diabetes where autoantibodies are not found, this number is very rare, usually up to 95% of new patients have type diabetes 1 has at least 1 positive autoantibody. IAA is also found in a number of other diseases such as: Graves, Hashimoto's thyroiditis, Addison's disease, chronic hepatitis, pernicious anemia, rheumatoid arthritis and lupus erythematosus.
It is also important to note that people with diabetes receiving insulin treatment may begin to develop antibodies against exogenous insulin (insulin injected into the body). At this time, the insulin anti-insulin antibody (IAA) test cannot distinguish between newly created antibodies and autoimmune antibodies. Therefore, IAA testing would not be appropriate in patients already receiving insulin therapy.
The IAA test is one of the autoantibody tests that aims to evaluate the classification of diabetes types such as type 1 and 1.5 or type 2. For the most accurate diagnosis, patients should go to the medical facilities for examination and appropriate tests by a doctor.
Currently, at Vinmec International General Hospital, there are full examination, screening and testing programs to diagnose diabetes. The entire process of examination, screening, determination of the condition and stage of the disease is carried out by experienced and well-trained specialists both at home and abroad. Besides, in order to improve service quality, in addition to fully equipped with the most modern facilities, at Vinmec, there are also packages of diabetes screening and hyperlipidemia so that customers can conveniently intensive examination and treatment.
For detailed information, you can go to Vinmec International General Hospital or register online.
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