This is an automatically translated article.
AskHello doctor!
I got a splash of serum that was positive for HBV virus in my eye.
Immediately after that, I went to the doctor and got tested, the test results for HBV antigen and antibody were negative. After that, she was vaccinated with Engerix B vaccine, according to the basic vaccination schedule (the second dose is 1 month after the first dose, the third dose is 6 months after the second dose). As far as I know, the hepatitis B vaccination schedule for newly exposed people is 7 days after the first dose. I didn't get any further advice so I was very worried, I don't know if such injection will completely prevent hepatitis B infection? How soon can I get tested again? Should I get the next shot 7 days after the first one? Or should I inject according to the original schedule? I hope the doctor can help me. I would like to thank you.
Anonymous question
Answer
Hello!
With the question "How soon should I be tested again to determine if I have HBV?", the doctor would like to answer you as follows:
HBsAg appears in the serum 1-10 weeks after acute exposure with HBV, present before clinical and subclinical symptoms. For patients recovering from acute infection, HBsAg will disappear after 4-6 months. Chronic HBV infection when HBsAg is present for more than 6 months. So to determine exactly whether you are infected with hepatitis B virus, you should take a test after 6 months. Regarding the issue of Hepatitis B vaccination for newly exposed people:
Currently, the vaccination schedule is 0-1-6 and 0-1-2-12. Response to vaccine (antibody production) includes many factors such as age, sex, obesity, chronic disease (such as kidney disease, immunodeficiency, smoking, diabetes mellitus) ...). It also depends on a number of factors such as injection site, needle depth. There are some views on increasing the dose of the vaccine or changing the schedule, but there are no specific recommendations for these views. Thus, whether it is completely preventable in my case is uncertain because it depends on quite a few factors. In addition, the administration of Hepatitis B Immune Globulin (HBIg) confers passive immunity against HBV. Known nonresponders and those with known poor response to the full HBV vaccination series should receive HBIg after exposure to high-risk HBV. Thank you for trusting Vinmec Health System, looking forward to meeting you directly for more detailed advice. Best regards!
Consulted by Master, Doctor Nguyen Thi Cam Tu - Department of General Internal Medicine - Vinmec Times City International General Hospital.
