Everything you need to know about the drug Albumin

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Albumin is a type of plasma protein found in the human body. The drug is prepared in the form of a solution for intravenous injection with 3 basic strengths, including 5% strength drug, 20% strength drug and 25% strength drug.

1. Composition of the drug Albumin

Albumin drug has the active ingredient name Albumin.
Brand names of the drug Albumin: BologRx, Albuked 5, Buminate, Human Albumin Grifols, Albumin-ZLB, Kedbumin, Plasbumin-5, Albuminar-25, Plasbumin-25.
The drug is prepared in the form of a solution for infusion with 3 concentrations: 5%, 20% and 25%.

2. Effects of the drug Albumin

Albumin is considered a type of plasma protein in the human body, accounting for 58% - 74% of total protein. The use of Albumin is to increase plasma volume or increase serum concentration, anti-hyperbilirubinemia to help the body grow safely and healthy.
In some cases such as shock due to excessive blood loss, decreased protein due to liver failure or treatment of burns or surgery, Albumin can be used. Besides, Albumin can be used in combination with some other drugs to support the treatment of some other diseases.
Albumin preparations do not have any effect on normal coagulation or increase coagulation and do not contain coagulation factors.

3. Designation

Patients with severe albumin deficiency, who are indicated to replace Albumin, include:
Patients with hypovolaemia Patients with cardiovascular collapse Cases of shock Patients with burns Patients with cirrhosis of the liver ascites Disease In addition, the drug Albumin is also used as an adjunct in some cases such as hemodialysis, acute respiratory failure in adults, cardiopulmonary surgery, neonatal hyperbilirubinemia ....

4. Contraindications

Albumin is contraindicated in the following cases:
Patients who are allergic to albumin-containing products Patients with heart failure Patients with kidney failure or fluid retention in the body Patients with prolonged severe anemia Patients with pulmonary edema Patients with hypertension Patients with esophageal varices

5. Dosage

Albumin is usually given as an injection. Before administration to the patient, the drug may be administered intravenously without dilution or may be diluted with normal saline or 5% dextrose.
For adults:
Albumin 5% drug: in case the patient is not in excessive shock, administer 500ml or 250ml IV at a rate of 1-2ml/min in the starting dose. Albumin 5% is used in the following cases: Patients with liver disease Patients with burns Patients with shock Volume depletion Patients with hypoproteinemia Drugs Albumin 25%: to reduce edema, 200-300ml may be needed for patient. To avoid circulatory overload, within 30 to 45 minutes, no more than 100 ml of 25% albumin should be administered more rapidly than 100 ml IV. Albumin 25% is used in the following cases: Patients with acute liver failure Patients with burns Patients with acute nephritis Patients with advanced respiratory distress syndrome Patients with liver transplantation or surgery Patients with hypoproteinemia Newborn with hemolytic disease Hemodialysis patient Shock volume reduction
For children: 500-1000mg/kg intravenously or 10-20ml/kg intravenously for young children, including newborns (under 28 days old). For children, do not inject more than 250g in 48 hours or more than 6g/hour per day.

6. Side effects of the drug Albumin

When using Albumin, you may experience some unwanted effects, usually these effects are rare and do not require treatment, such as:
Lowering blood pressure Appearance of erythema, hives urticaria, itching, edema Fever, chills Headache Appears bronchospasm Vomiting, nausea, vomiting Increased salivation Not everyone using the drug will experience the above side effects, so when If you see any unusual signs, you need to notify your doctor immediately for timely treatment.

7. Be careful when taking Albumin

When using the drug, the patient needs to be rehydrated. Need to add electrolytes to the patient if more than 200ml is used.
Although there are no studies showing the risk of using albumin for pregnant and lactating women, in this case, the drug should only be used when absolutely necessary and in consultation with your doctor. doctor before use to ensure safety.

8. Notes before taking Albumin

Before taking the medicine, you need to discuss with your doctor some information such as:
Have you ever had an allergic reaction to any of the ingredients If you have anemia, kidney failure or heart failure Talk to your doctor all medicines you are taking You are pregnant or breast-feeding Talk to your doctor about stopping or changing the dose

9. How to store Albumin

If albumin is stored at a temperature not exceeding 30 degrees Celsius, the drug can be used for 3 years. Vials may crack and contaminate because freezing should be avoided. Only use the medicine within 4 hours of opening and discard the rest.

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