This is an automatically translated article.
The article was professionally consulted by Doctor Vo Ha Bang Suong - Doctor of Medicine - Department of Medical Examination & Internal Medicine - Vinmec Phu Quoc International General Hospital. The doctor has more than 15 years of experience in the treatment of internal diseases.Among the common medical diseases, rheumatoid arthritis is a disease of the musculoskeletal system of the body, chronic in nature and should be treated promptly to avoid unwanted complications, affecting the quality of life. life. To be able to detect this pathology during a general physical examination, it is necessary to perform an RF test to evaluate this disease.
1. What is Rheumatoid Arthritis?
Rheumatoid arthritis is one of the most common autoimmune diseases today, with a chronic nature and a rather complicated course. Depending on the stage of the disease, there will be manifestations in the joints, extra-articular or throughout the body of the patient.The cause of rheumatoid arthritis has so far not been confirmed by any research, but some suggest that the disease is related to the infection of the body as well as the patient's local factors. such as female gender, middle age, HLA... and problems related to immune response disorders in patients. In terms of pathogenesis, rheumatoid arthritis occurs due to the activity of B lymphocytes, T lymphocytes, macrophages and autoantibodies such as anti-CCP, RF, cytokines such as TNFα, IL6, IL1 ...
In order to accurately diagnose rheumatoid arthritis, the patient must have symptoms of the disease in many joint locations and the time to manifest these symptoms usually has to last more than 6 weeks. Symptoms of rheumatoid arthritis include:
Morning stiffness, stiffness lasting more than 1 hour Inflammation of at least 3 groups of joints including soft swelling, effusion at least 3 out of 14 joint groups such as proximal joints hand, knuckle, wrist joint....; Arthritis of the hand, swelling of at least one of the joints, such as the wrist, proximal, or metaphyseal joints; Inflammation of bilateral symmetrical joints; Appearance of some abnormal particles under the skin; Presence of rheumatoid factor RF in serum; When taking X-ray films of the joints of the hands and wrists, the image shows an erosional lesion, a cavity-shaped lesion, a bone head defect, or a narrow joint space and there is a loss of minerals in the head of the bone. SEE ALSO: Is knee pain when changing weather a sign of rheumatoid arthritis?
Viêm khớp dạng thấp là căn bệnh rất phổ biến hiện nay
2. RF . Low Form Factor Evaluation
Besides the paraclinical tests for the diagnosis of rheumatoid arthritis such as: blood test, erythrocyte sedimentation rate test, CRP, liver and kidney function test, X-ray of the heart, lungs, electrocardiogram ECG... then the RF test plays an extremely important role in the diagnosis of this pathology. Rheumatoid Factor RF or Rheumatoid Factor is a test done to check for the presence of RF antibodies in the blood of patients with suspected rheumatoid arthritis. This is one of the types of antibodies produced by the human immune system. It has the ability to self-generate, attacking the body's own tissues and cells due to the confusion when recognizing the body's organ tissues with other foreign agents entering the body.Under normal conditions, rheumatoid factor RF is within the permissible limit of less than 12U/mL, but when this limit is exceeded, there is destruction of cells in the patient's body, or is a symptom of rheumatoid arthritis.
Evaluation of rheumatoid factor may give some of the following results:
Rheumatoid factor RF < 12 U/mL: patient is in normal condition; Rheumatoid factor RF ≥ 14 U/mL: at this time, the amount of RF in the patient's body exceeds the allowable limit, which can be thought of some diseases such as rheumatoid arthritis, Sjogren's syndrome; In case the evaluation of rheumatoid factor is negative but the patient still has some clinical symptoms of rheumatoid arthritis, a few other tests such as Anti CCP, erythrocyte sedimentation rate, X-ray film may be indicated. – optical... for more precise assertion. In addition, when performing rheumatoid factor assessment, it is necessary to consider a number of factors that can affect test results such as:
Age: elderly patients often have factor test results. RF low form is higher than normal people. Patients who use certain drugs such as non-steroidal anti-inflammatory drugs, Aspirin may also affect test results. may result in a positive RF rheumatoid factor test. In patients with certain medical conditions such as fatty blood, cloudy serum, the results of rheumatoid factor assessment will also be affected. MORE: Rheumatoid Factor (RF) Test in Rheumatoid Arthritis
Xét nghiệm yếu tố RF rất quan trọng trong việc chẩn đoán bệnh
3. Conclusion
The evaluation of rheumatoid factor RF is extremely important and necessary in diagnosing rheumatoid arthritis as well as excluding the possibility of other diseases when the patient has symptoms suspicious of rheumatoid arthritis. short.However, when performing RF rheumatoid factor test, it is also necessary to pay attention to the patient's current condition so that the test results are most accurate, thereby making a definite diagnosis on the patient. Therefore, it is necessary to perform tests at reputable medical facilities as well as have adequate equipment for conducting these paraclinical tests.
To detect rheumatoid arthritis early, you should check your general health regularly. The results of the biochemical test of the RF index will tell the patient whether he has rheumatoid arthritis or not. Currently, Vinmec International General Hospital has general health checkup packages suitable for each age, gender and individual needs of customers with a reasonable price policy, including:
General health checkup package diamond general health checkup package Vip special health checkup package Comprehensive general health checkup package Standard general health checkup package Patient's examination results will be returned to your home. After receiving the results of the general health examination, if you detect diseases that require intensive examination and treatment, you can use services from other specialties at the Hospital with quality treatment and services. outstanding customer service.
Customers can call hotlines of hospitals or register for online consultation with Vinmec via the system's website.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
