Betaloc Zok 25mg is a beta-blocker commonly used to treat cardiovascular conditions and hypertension. As a prescription medication, it should be taken under the guidance of a doctor or pharmacist to ensure safety.
1. What is Betaloc Zok 25mg? Chemical composition
Betaloc Zok 25mg is used to treat cardiovascular and hypertension-related conditions. This medication is available in tablet form, with each tablet weighing 25mg. The tablets are white and packaged in blister packs containing 14 tablets each.
Each Betaloc Zok 25mg tablet contains 23.75mg or 47.5mg of metoprolol succinate, equivalent to 25mg or 50mg of metoprolol tartrate. This compound belongs to the selective beta-1 receptor blocker group, which contributes to its primary therapeutic effects.
2. Conditions treated with Betaloc Zok 25mg
With metoprolol as its active ingredient, Betaloc Zok 25mg is effective in treating:
- Hypertension: Helps lower blood pressure, reducing cardiovascular mortality risk and minimizing organ damage.
- Angina: Treats stable chronic heart failure caused by left ventricular dysfunction and prevents death or reinfarction after acute myocardial infarction.
- Arrhythmias (especially supraventricular tachycardia): Reduces ventricular rate in atrial fibrillation and suppresses ventricular extrasystoles.
- Heart dysfunction with palpitations: Relieves palpitations associated with heart dysfunction.
- Migraine prophylaxis: Can also be used to prevent migraine headaches.
3. Dosage and administration
Betaloc Zok 25mg is formulated as tablets and administered orally. The tablets should be swallowed whole or split in half. They should not be chewed or crushed, as this may make them difficult to consume. Betaloc Zok 25mg is typically prescribed as a single daily dose and is best taken in the morning.
The dosage is determined by the patient's condition and overall health, with specific recommendations as follows:
- Hypertension treatment: Patients with high blood pressure are advised to take 50mg once daily. The dosage may be increased to 100-200mg once daily or combined with other antihypertensive medications if the initial dose is insufficient.
- Angina treatment: A dosage of 100-200mg once daily is recommended. It may be combined with other angina treatments for improved effectiveness.
- Stable heart failure (Class II): During the first two weeks, a dosage of 25mg once daily is prescribed. After two weeks, the dose may be increased to 50mg once daily, then doubled every two weeks if necessary. For long-term treatment, the optimal dose is 200mg once daily.
- Stable heart failure (Class III-IV): Initially, patients take 12.5mg once daily. After 1-2 weeks, the dosage may be increased to 25mg once daily, followed by 50mg once daily after another two weeks. Further increases can be made every two weeks but should not exceed 200mg once daily. All dosage adjustments must be under medical supervision.
- Arrhythmia treatment: A dosage of 50mg 2-3 times daily is recommended. For severe cases, the dose may be increased to 300mg daily, divided into multiple doses.
- Myocardial infarction treatment: Betaloc Zok 25mg is prescribed at 50mg every six hours. It should be administered 15 minutes after injection and within a maximum of 48 hours (ideally within 12 hours) of the onset of chest pain. For long-term use or poor tolerance, a dose of 200mg once daily is suggested.
- Palpitations and functional cardiac disorders: The manufacturer recommends a dose of 100mg once daily, which may be increased to 200mg if needed.
The above dosages are intended for adults. Betaloc Zok 25mg should not be used for children. Dosage and administration must be determined by a physician or healthcare professional. Patients should never self-medicate without medical approval, as improper use can lead to serious consequences, including life-threatening conditions.
4. Side effects
Betaloc Zok 25mg is effective in treating cardiovascular and blood pressure-related conditions. However, caution is required as it may cause some unwanted side effects, such as:
- Cardiovascular system: Betaloc Zok 25mg can slow heart rate, lower blood pressure, cause palpitations, and, less commonly, transient heart failure, first-degree atrioventricular block, swelling, and chest pain.
- Central nervous system: Patients may experience fatigue, dizziness, headache, paresthesia, and muscle cramps after taking Betaloc Zok 25mg.
- Digestive system: Overdose symptoms include abdominal pain, nausea, diarrhea, and constipation.
- Thrombocytopenia (low platelet count).
- Hepatitis.
- Joint pain.
- Weight gain.
- Depression, difficulty concentrating, memory impairment, confusion, and hallucinations.
- Drowsiness or insomnia, restlessness.
- Visual disturbances.
- Tinnitus, and taste disturbances.
The above list does not include all possible side effects of Betaloc Zok 25mg. Patients may experience other side effects not mentioned here. Therefore, it is essential to monitor for any unusual signs while using the medication.
5. Precautions
When using Betaloc Zok, patients should note the following:
- Gradually reduce the dosage; do not stop taking the medication abruptly.
- Do not use Betaloc Zok 25mg in combination with intravenous Verapamil-type calcium channel blockers.
- Patients with congestive heart failure should not use Betaloc Zok 25mg until the congestion is resolved.
- Patients with severe cardiac dysfunction, especially those with cardiac activity dependent on the sympathetic system, should use the medication with caution. Betaloc Zok 25mg can reduce sympathetic activity and may worsen bradycardia, peripheral circulatory disorders, and anaphylactic shock.
- Betaloc Zok 25mg may mask or reduce the symptoms of thyroid toxicity. Therefore, thyroid function should be closely monitored while using the medication.
- The medication may exacerbate psoriasis, so careful consideration is required before use.
- Do not use Betaloc Zok 25mg in patients with galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption.
- Inform your doctor if you are using Betaloc Zok 25mg before surgery. Do not stop the medication on your own before surgery.
- Do not start treatment with high doses of Betaloc Zok 25mg in patients undergoing non-cardiac surgery. This can cause bradycardia, hypotension, and stroke, which may lead to death in individuals with cardiovascular risk factors.
- Pregnant or breastfeeding women should not use Betaloc Zok 25mg unless absolutely necessary.
6. Potential drug interactions
Drug interactions can occur in two cases: positive and negative. Positive interactions will enhance the effectiveness of treatment and shorten the treatment time for patients. However, if drugs are not combined correctly, they can result in dangerous consequences. Not only will they fail to alleviate symptoms, but they may worsen the condition and even pose a risk to life. Therefore, it is important to be aware of the drugs that cause negative interactions with Betaloc Zok 25mg.
Below are the drugs that negatively interact when combined with Betaloc Zok 25mg:
- Sympathetic ganglion inhibitors and other beta-receptor antagonists;
- MAO inhibitors (IMAO);
- Calcium channel blockers, especially verapamil and diltiazem groups;
- Antiarrhythmic drugs, especially quinidine and amiodarone;
- Digitalis glycoside group drugs;
- Inhalation anesthetics;
- Indomethacin or prostaglandins;
- Oral diabetes medications.
No research has shown any impact of food on the effects of Betaloc Zok 25mg. Therefore, patients should follow a diet based on their medical condition. Cardiovascular patients should avoid excessive salt, and diabetic patients should limit sugar intake.
Thus, Betaloc Zok 25mg is an effective medication for treating cardiovascular diseases and hypertension, belonging to the beta-blocker group. We hope that the above information helps readers use the medication effectively and safely.
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