Instructions for use Cimetidine 200mg

Peptic ulcer or gastroesophageal reflux disease is a very common disease today. Therefore, the demand for drugs to treat this disease is increasing day by day. One of the popular drugs today is Cimetidine 200mg. So what are the instructions for using Cimetidine 200mg?

Cimetidine medicine 200mg has the ingredient Cimetidine with 200mg content, this is the active ingredient in the group of antacids, anti-reflux and anti-ulcer drugs. Cimetidine competitively inhibits histamine at the H2-receptor of gastric parietal cells, thereby inhibiting gastric acid secretion during fasting.
Cimetidine 200mg medicine is used for short-term treatment of advanced gastric and duodenal ulcers, gastroesophageal reflux disease causing esophageal ulcers, maintenance treatment of duodenal ulcers with low dose after ulceration. The ulcer has been relatively healed. In addition, Cimetidine 200mg is also used in Zollinger - Ellison syndrome, multiple endocrine neoplasia, prophylactic treatment of gastrointestinal bleeding due to esophageal ulcer, gastric ulcer, duodenal ulcer. ..
Cimetindin can be prepared in many different dosage forms:
Tablets: 200mg, 300mg, 400mg, 800mg; Effervescent tablets: 200mg, 300mg, 400mg, 800mg; Syrup: 5ml equivalent to Cimetindin 200mg, 300mg; Injections: each 2ml tube of cimetidine hydrochloride contains 300mg cimetidine equivalent (can customize the dose of cimetidine 200mg injection as prescribed by the treating doctor); 400mg infusion in 100ml of 0.9% sodium chloride.

Patients can refer to the instructions for using Cimetidine 200mg below in combination with the indications and instructions of the doctor to bring the highest efficiency. Like other drugs, before starting to use the patient should consult and follow the advice of a doctor or pharmacist.
2.1. Dosage of Cimetidine Drug Dosage Cimetidine 200mg for adults:
Indications in peptic ulcer: Take a single dose of 800mg/day in the evening before going to bed. Duration of treatment is 4 weeks for duodenal ulcer and 6 weeks for gastric ulcer. After that, a maintenance dose of 400mg/day can be used before going to bed; Indications in gastroesophageal reflux disease: Patients take 400mg/time, 4 times/day. The maximum allowable dose is 2.4g/day; Indications in upper gastrointestinal ulcers due to stress: Oral dose of 200-400mg / time, every 4-6 hours. Dosage of Cimetidine 200mg for children:
Full-term neonates and normal kidney function: Dosage is 10–15mg/kg/day and only used when absolutely necessary; Children over 1 year old can use a dose of 25-30mg/kg/day, divided into several doses.

2.2. How to use Cimetidine 200mg Patients should use Cimetidine 200mg as directed on the instruction sheet or as directed by a doctor. Absolutely do not arbitrarily use in large or smaller doses or use for a longer time than directed.
The dose of the drug may vary depending on the condition, the severity of the disease and the age of the patient. If Cimetidine 200mg is used for children with renal failure, the dose must be adjusted down to 10–15mg/kg/day and administered every 8 hours.

Patients may encounter some common side effects during the use of Cimetidine 200mg, including:
Diarrhea; Headache; Drowsiness or confusion is reversible; Depression or agitation, restlessness, hallucinations; Disorientation; Breast enlargement in men. Besides, some undesirable effects of Cimetidine 200mg are less common such as:
Reversible impotence in men; Rash; Temporary increase in liver enzymes; Increased blood creatinine; Fever; Allergies, including anaphylaxis; Hypersensitivity vasculitis. Some rare but serious side effects that the patient must quickly notify the doctor for timely treatment, include:
Slow or fast pulse; Cardiac arrhythmias such as atrioventricular block; Neutropenia or agranulocytosis, thrombocytopenia, pancytopenia, non-regenerative anemia; Chronic hepatitis, jaundice, liver dysfunction; Pancreatitis; Interstitial nephritis ; urinary retention; Polymyositis; Hair loss, baldness.

Before using Cimetidine 200mg, patients need to talk to their doctor or pharmacist if:
A history of being allergic to any of the ingredients in the drug; Are taking certain medications for other medical conditions, including prescription and non-prescription drugs; Have ever had or are suffering from liver disease, kidney disease. Before treating stomach ulcers with Cimetidine 200mg, patients need to be excluded the possibility of cancer, because the use of this drug can mask symptoms and make diagnosis difficult.
Some things to keep in mind when taking Cimetidine 200mg in special cases:
Pregnant women: Cimetidine 200mg can cross the placenta. Although there is no evidence to show the possibility of harm to the fetus, but to ensure safety, this person should avoid using this drug; Lactation: Cimetidine 200mg is likely to be excreted in breast milk at concentrations higher than those in maternal plasma. Although no side effects have been recorded for breastfed babies, women who are breastfeeding should limit the use of Cimetidine 200mg;

Cimetidine 200mg may affect the ability of certain other medicines you are taking or increase the risk of unwanted side effects. To prevent drug interactions, it is best for patients to make a list of all medications they are taking (including prescription drugs, nonprescription drugs, herbs, supplements) and notify the doctor. or pharmacist.
Cimetidine 200mg drug can interact with some drugs such as:
Metformin; Warfarin; Quinidine; Procainamide, lidocaine, propranolol; Nifedipine; Phenytoin, valproic acid; Theophylline. In addition, the body will reduce the absorption of Cimetidine 200mg if copper is used with drugs containing sodium, magnesium, aluminum, and calcium.
Besides drug interactions, Cimetidine 200mg can also interact with food, alcohol and tobacco to varying degrees. Patients should consult their physician regarding the use of this medication and its interactions with food, alcohol, and tobacco.