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Orlistat 120mg drug belongs to the group of gastrointestinal drugs, used to treat obesity, to help prevent cholesterol absorption and reduce blood cholesterol levels. So what are the uses of Orlistat and in what cases is it indicated?
1. What is Orlistat 120mg?
Orlistat contains the main ingredient, Orlistat 120mg, which is prepared in the form of orlistat pellets 50% and other excipients such as Lactose, croscarmellose sodium, sodium stearate, sodium lauryl sulfate povidone K30 just enough for 1 tablet. The drug is prepared in the form of hard capsules for users, packed in the form of boxes, including 2 blisters x 21 tablets.
2. Uses of Orlistat
Mechanism of action of the drug is that when eating food into the body, the fat in that diet needs to be broken down so that the body can absorb it. Active ingredient Orlistat works by blocking enzymes that break down fats in the diet. This unresolved fat is then eliminated from the body.
Orlistat weight loss drug is indicated for the following cases:
People in the process of obesity treatment Prevent weight gain in patients with BMI greater than 30 kg/m2 Overweight patients with index BMI greater than 28kg/m2 with risk factors (such as hypertension, diabetes, hyperlipidemia) is combining Orlistat with a low-calorie diet. Orlistat weight loss pills are contraindicated for use in the following cases:
People with hypersensitivity or severe allergy to orlistat or any ingredient in the drug. Patients with cholestasis or chronic malabsorption syndrome. People who are being treated concurrently with the active ingredient ciclosporin. Target users are pregnant and lactating women. Patients receiving concomitant treatment with warfarin or other oral anticoagulants.
3. Usage and dosage of Orlistat 120mg
Orlistat is a drug that is prepared in the form of a hard capsule that should be taken orally. Users should drink with a sufficient amount of water, do not break, chew or crush the tablet when taking it. The drug should be taken immediately before, during or 1 hour after the main meal. If the user misses a meal or has a fat-free meal, there is no need to take Orlistat 120.
The drug should be taken as prescribed by a doctor or can refer to the following dosage:
Used to treat obesity, prevent weight gain in adults, adolescents older than 12 years: dose 120mg x 3 times/day. For overweight people from 18 years of age and older: dose 60mg x 3 times/day Note: Absolutely do not use more than 3 times/day. If after 12 weeks of treatment, the user does not lose weight, it is necessary to consult a doctor or pharmacist immediately. If necessary, stop using the drug to avoid unwanted side effects.
In case of missed dose, you should skip the missed dose and continue taking the next dose at the same time as indicated. Do not take a double dose to replenish the missed dose. However, users should note taking the medicine regularly to achieve the best effect of the drug.
If you accidentally overdose and have serious side effects, you need to immediately notify your doctor or take them to the nearest medical facility for timely examination.
2. Undesirable side effects of Orlistat 120mg
Common symptoms:
Mental disorders, anxiety Lower respiratory tract infections Digestive system disorders: rectal discomfort/pain, urinary incontinence, soft tissue, abdominal bloating. Urinary tract infections Menstrual disorders: irregular periods Fatigue Very common symptoms:
Headache, flu, or low blood sugar Upper respiratory tract infections Digestive system disorders Gastrointestinal: abdominal pain, discomfort, flatulence, defecation, acute diarrhea, loose stools, mucus sputum in the rectum, increased defecation, fatty urination. Note: When experiencing one of the above symptoms, users need to stop taking the drug immediately and notify their treating doctor or go to the nearest hospital for timely diagnosis and treatment.
3. Orlistat 120mg . drug interactions
Some interactions with Orlistat 120mg are as follows:
Drug interaction studies have shown a decrease in plasma concentrations when orlistat is co-administered with ciclosporin. International normalized ratio (INR) should be monitored when warfarin or other anticoagulants are co-administered with Orlistat. When treated with orlistat has the ability to reduce the absorption of vitamins A, D, E, K, and fat-soluble vitamins. Co-administration of Orlistat with levothyroxine causes hypothyroidism. This case should be monitored for changes in thyroid function. It is recommended that levothyroxine and orlistat be administered at least 4 hours apart. This drug reduces the plasma concentration of amiodarone. Convulsions may occur when Orlistat is used concurrently with antiepileptic drugs such as valproate, lamotrigine. Because Orlistat reduces the absorption of antiepileptic drugs, which leads to seizures. Orlistat may decrease the effectiveness of oral contraceptives, and in rare cases may lead to an unwanted pregnancy. HIV antiretrovirals, antipsychotics, antidepressants, and benzodiazepines: impaired efficacy of HIV antiretrovirals, antidepressants, benzodiazepines, and antipsychotics (including lithium) has been reported when co-administered with orlistat in previously well controlled patients. Therefore, treatment with orlistat should be initiated, after careful consideration of the possible effect on these patients.
4. Some notes when using Orlistat 120mg
The studies in this report indicate that Orlistat 120mg has no effect on the ability to drive and use machines, allowing this subject to be used. The drug should be used with extreme caution in patients with a history of hyperoxaluria, calcium oxalate stones in the kidney, patients with type II diabetes mellitus, the elderly, liver and kidney failure. Users need to combine both a nutritionally balanced diet or regimen with regular exercise when using the drug. After discontinuing the drug, users still need to continue with their diet and exercise regimen to maintain the desired body shape. The safety of the drug has not been established in children younger than 12 years of age. Hopefully, the information shared about the uses, usage and some necessary notes about Orlistat 120mg will help users understand more details and get the best effect when used.
