What is Bilaxten 20mg?

Bilaxten is a drug belonging to the group of antihistamines and is used for systemic use in allergic cases for adults and children over 12 years of age. This is a long-acting, long-acting allergy-related medication that has been studied without drowsiness in the majority of people.

Bilaxten has the main active ingredient Bilastine 20mg. Bilastine is a long-acting, non-drowsy, antihistamine belonging to the group of antihistamines.
When the body is exposed to an allergen or so-called allergen, the body releases histamine and other mediators from IgE antibody-mediated mast cell release in the mucosa and on the skin. skin. Histamine has the effect of causing the main manifestations of the disease such as skin rashes, sneezing, runny nose ... so the use of antihistamines is used to treat allergic conditions. These drugs have been shown to be effective in the symptomatic treatment of allergic diseases, and bilastine is one of them.

The main active ingredient bilastine in the drug has been studied to inhibit the reactions of itching, pimples, papules, skin rashes caused by histamine within 24 hours after using a dose. Additionally, in clinical trials conducted in adults and adolescents with year-round allergic rhinitis, bilastine 20 mg once daily for approximately 14 to 28 days was effective. It is very effective in relieving symptoms such as sneezing, stuffy nose, runny nose, itchy nose, watery eyes and red eyes.
Therefore, Bilastine is used in the symptomatic treatment of people with allergic rhinitis (seasonal and year round) or cases of urticaria.
This drug should be noted not to be used in patients who have a hypersensitivity reaction to bilastine or any of the excipients contained in the drug.

The drug is used about 1 hour before or 2 hours after eating with the right dose:
For users over 12 years old: Take 1 tablet of Bilaxten 20mg once daily. This dose does not need to adjust the dose for the elderly, patients with renal impairment. For patients with hepatic impairment: In humans, bilastine is not metabolized by the liver. Since the results of drug studies in patients with renal impairment show that the renal route of elimination is the major route of elimination, hepatobiliary excretion contributes only a very small part to the elimination of bilastine. . Alterations in liver function are unlikely to significantly alter the pharmacokinetics of bilastine in clinical practice and do not pose a risk of blood retention. Since then, for these patients there is no need to change the dose. Children under 12 years of age are not recommended to use this medicine. Currently, there is no safety evidence for the use of this medicine in children under 12 years of age.

When taking the drug may cause some unwanted effects including headache, dizziness, fatigue. Sometimes still cause drowsiness, palpitations, tachycardia. In patients with severe or moderate renal impairment, bilastine should not be used concomitantly with glycoprotein P inhibitors such as ketoconazole, erythromycin, ritonavir cyclosporin or diltiazem may increase the plasma concentration of Bilastine, thereby increasing the risk of adverse reactions. Drowsiness is a rare but still possible side effect. Therefore, those who drive and operate machinery should be careful. For pregnant women, there are insufficient data on safety, so the use of Bilastine should be avoided during pregnancy. Breastfeeding also has not been studied to evaluate whether the drug passes into breast milk, so to be safe, it should be avoided while breastfeeding. Interactions with food and drink: Food can reduce the oral bioavailability of Bilastine by about 30%, so it should be taken away from meals; When taking Bilastine 20mg with grapefruit juice reduces the bioavailability of the drug by 30% and this phenomenon can occur when taking other juices. The drug can interact with some drugs such as Ketoconazole, Erythromycin, Diltiazem, Lorazepam...so it should be avoided. In case of overdose: You often develop symptoms of overdose when taking a dose of about 100mg within a few days, when you develop symptoms similar to side effects and may change the QT interval on the electrocardiogram. When overdosage will be treated according to the patient's symptoms, currently there is no antidote to bilastine. If you miss a dose, take it as soon as you remember and as soon as possible. But if it's too close to your next dose, you can skip it. Bilaxten is a drug that is used systemically with the main effect of being an antihistamine produced during the reaction to an allergen. In cases of allergies caused by allergies, it is best to avoid contact with the allergen, but if you do not know the cause, you can use antihistamines such as bilaxten to treat unpleasant symptoms.