Uses of Cefrobactum


What is Cefrobactum? Cefrobactum contains the main ingredients Cefoperazone sodium and Sulbactam sodium. Medicines are commonly used in the treatment of infections. Let's learn about the use of Cefrobactum in the article below.

1. Uses of Cefrobactum


Cefrobactum is a semi-synthetic 3rd generation cephalosporin antibiotic, administered parenterally, with bactericidal action through inhibition of bacterial cell growth and division.
Cefrobactum has broad-spectrum bactericidal activity, effective against gram-negative bacteria such as penicillinase-producing N. gonorrhoeae, Enterobacter, Citrobacter, Morganalle, Proteus, Providencia, Shigella, Salmonella, ...

2. Indications and contraindications to the drug Cefrobactum


Cefrobactum is usually indicated in the following cases:
Respiratory tract infections Urinary tract infections, hepatobiliary tract infections Peritoneal infections Gynecological infections Endocarditis Infections secondary to surgery, trauma Infections Meningitis blood. Absolutely do not use Cefrobactum for patients who are sensitive to any of the ingredients of the drug.

3. Dosage and how to use Cefrobactum


Cefrobactum is a prescription drug, so patients can only use it when prescribed by a doctor and must adhere to the treatment schedule, not to quit smoking, change dosage and route of medication. At the same time, do not share Cefrobactum with other people or give it to other people to use even if they have the same diagnosis.
Dosage:
Adults: 2-4g/day divided into 2 times Children: 40-80mg/day, divided into 2-4 times For severe and long-term infections:
Adults: 8g/day divided 2 times Children: 160mg/day divided into 2-4 times. Cefrobactum is prepared in the form of a powder for injection and administered by injection, intravenous infusion.
When you miss a dose, take an alternate dose. If it is almost time for the next dose, skip the missed dose, do not increase the dose, or double the dose to make up for the missed dose.
When an overdose is suspected, it is necessary to quickly contact medical staff for timely treatment.

4. Undesirable effects


In addition to the therapeutic effect, Cefrobactum drug may cause some unwanted effects during use such as shock, hypersensitivity, acute renal failure, fever, eosinophilia, decrease in Hb and Hematocrit values, elevated liver enzymes, mild and transient elevations in serum phosphates, GI effects, diarrhea, loose stools, nausea, vomiting, transient increases in BUN and Creatinine levels, ...
In addition, patients may experience Other undesirable effects have not been reported or studied. Therefore, it is necessary to closely monitor the patient during treatment and immediately contact medical staff when there are any abnormal signs.

5. Drug interactions


When treating disease with many different drugs, each drug has different ingredients, there may be interactions between ingredients in the drug or interactions between drugs and foods, affecting the health of the patient. bioavailability, effects, and even increased side effects of the drug. In addition, some other diseases such as immunodeficiency, diabetes, cancer, liver failure, kidney failure, ... can also affect the effectiveness of the drug.
Therefore, in order to use Cefrobactum safely and effectively, patients need to list and inform their doctor about all medications they are taking as well as their current health status. At the same time, it is necessary to discuss with your doctor about the use of certain foods and drinks (such as alcohol, stimulants, fermented foods during treatment with Cefrobactum. with Cefrobactum as other antibiotics, diuretics, anticoagulants
Coadministration of Cefrobactum and Aminoglycoside antibiotics may increase the risk of nephrotoxicity. Concomitant use of Cefrobactum and Heparin, Warfarin may reduce prothrombin markedly and prolonged bleeding time.

6. Some notes when using Cefrobactum


There is not enough evidence on the safety of using Cefrobactum in pregnant and lactating women, so Cefrobactum should not be used in these two subjects. The safety of Cefrobactum in children has not been reported, so it should be used with caution. Cefrobactum should be used with caution in patients with a history of hypersensitivity to penicillins or cephalosporins, allergic conditions, bronchial asthma, urticaria, rash, severe renal impairment, the elderly, poor physical condition, and patients. poor diet, must be fed parenteral nutrition. Limit alcohol use while taking Cefrobactum.

7. Preservation of drugs


Store Cefrobactum in the original manufacturer's packaging, in a cool, clean place away from direct sunlight.
Keep Cefrobactum out of reach of children as well as pets, avoid them not knowing how to chew can cause serious unwanted effects.
Do not use Cefrobactum drugs that have expired or show signs of change in color, properties, taste, no labels.

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