This is an automatically translated article.
Barzfin belongs to the group of drugs for the gastrointestinal tract. The drug is indicated for the treatment of ulcers in the colon and rectum. Let's find out what Barzfin does?
1. What is Barzfin?
Barzfin medicine contains Mesalazine ingredient 1g and other excipients just enough for 1 tablet. The drug is prepared in the form of suppositories placed rectally, packing specifications are in the form of a box of 2 blisters, each blister has 5 tablets.
Barzfin contains the active ingredient Mesalazine, which has long been used in the treatment of ulcerative colitis and Crohn's disease. In patients with inflammatory bowel disease, there are manifestations such as increased leukocyte migration, abnormal cytokine production, increased production of arachidonic acid metabolites, and increased free radical formation in inflamed intestinal tissue. Mesalazine inhibits leukocyte chemotaxis, reduces cytokine and leukotriene production, and scavenges free radicals.
2. What does Barzfin do?
Barzfin is indicated for the treatment of the following cases:
Ulcerative colitis, Crohn's disease. In addition, the drug Barzfin is contraindicated in the following cases:
Patients are allergic to active ingredients Mesalazine and other excipients in the composition of the drug.
3. Dosage and how to use Barzfin
3.1. How to use Barzfin drug is in the form of a suppository, so patients use it by placing it in the rectum. The medicine is packaged in an aluminum bag, which the patient should remove immediately before use.
The way to put the suppository into the rectum is as follows:
Step 1: The patient should have a bowel movement before placing this medicine in the colon
Step 2: Remove the aluminum bag
Step 3: Shake the plastic bottle well before using
Step 4: Twist the cap of the vial once.
Step 5: Place one of your hands in the included plastic bag and hold the vial.
Step 6: Prepare a position to put the medicine, such as lying on the left side.
Step 7: Carefully insert the tip of the vial into the rectum and squeeze the medicine out slowly. Can be used multiple times.
Step 8: Pull out the tip of the vial while still squeezing the medicine
Step 9: Hold the above position for 5 to 10 minutes or until stimulation.
Step 10: Roll the condom onto the vial before discarding.
3.2. Dosage Active Ulcerative Colitis:
Adults: Take 1g (1 tablet), 1 to 2 times daily. Elderly: No dose reduction is necessary, but renal function should be checked prior to administration. Ulcerative colitis maintenance treatment:
Adults: Each patient has a different dose, but the maximum recommended dose is 2g/day, divided into several times a day. Children over 2 years old: Dosage for each pediatric patient, the usual dose is 20-30mg/kg body weight, divided into several times a day. Active Crohn's disease and maintenance therapy:
Dosage for each patient, but the maximum recommended dose is 4.5g/day in divided doses. Children over 2 years old: Dosage for each pediatric patient, the usual dose is 20-30mg/kg body weight, divided into several times a day. Elderly: No dose reduction is necessary, but renal function should be checked prior to administration. Note: The above dosage is only the recommended dosage. The treating doctor depends on the condition of each patient to prescribe the appropriate dose.
4. Side effects of the drug Barzfin
Doctors always consider between the benefits that Barzfin brings to the patient and the possible risk of side effects to prescribe the appropriate medication.
Some unwanted effects that may occur when taking Barzfin include:
Local reactions such as itching, discomfort and the need to defecate after placing the drug. Headache, diarrhea, nausea, vomiting, abdominal pain, rash. Allergic reactions and mild fever due to the drug. In case the patient has rare side effects that are not mentioned in the instruction sheet. Inform your doctor or medical officer immediately if you suspect any side effects of Barzfin.
5. Barzfin drug interactions
Some interactions may occur between drugs when used in combination with Barzfin:
Concomitant use of Barzfin with Azathioprine or 6-Mecaptopurine may increase the risk of bone marrow depression (such as leukopenia, decreased urination, anemia, thrombocytopenia or pancytopenia). Concomitant use with other drugs known to be nephrotoxic, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and azathioprine, may increase the risk of nephrotoxicity. To avoid interactions, before being prescribed Barzfin, patients should inform their doctor about all the drugs they are using, including functional foods. The doctor will base on that to prescribe the appropriate Barzfin.
6. Notes when using Barzfin
Some notes when the patient takes Barzfin medicine as follows:
The patient should take the drug in the correct route and dose as prescribed by the doctor. Use with caution in patients with liver and kidney failure. Patients should be tested and assessed for liver and kidney function before starting the drug. Pregnant women: When using Barzfin medicine can leave serious consequences for the fetus such as miscarriage, malformation,... Therefore, this drug should not be used, unless absolutely necessary for benefits. therapeutic benefits of the mother. Breast-feeding: Although there are no adequate reports of possible risks. However, to limit the potential risk of breastfeeding, the drug should not be used unless directed by a doctor. In case the patient has to take medicine for the treatment, breast-feeding can be stopped.
7. What to do in case of missed dose or overdose of Barzfin?
When a dose is forgotten, the patient should take it as soon as he remembers, the drug can also be used 1-2 hours from the usual time of taking the medicine. If it is almost time for your next dose, skip the missed dose. Do not take a double dose to make up for a missed dose. In case of an overdose of Barzfin, the patient should stop taking the drug and notify the treating doctor. Immediately take the patient to the nearest hospital when the condition worsens. Patients need to bring a prescription or medicine box so that the doctor can grasp the information and handle it quickly and promptly. Above is information about uses, dosage and precautions when using Barzfin. To ensure safety for health and maximize the effectiveness of treatment, patients need to take Barzfin exactly as directed by their doctor. Note, Barzfin is a prescription drug, patients absolutely must not use it without a prescription from a specialist.
