Complications of severe serotonin syndrome can cause metabolic acidosis, rhabdomyolysis, acute kidney injury, seizures, disseminated intravascular coagulation, or death. Complications can be caused by hyperthermia and excessive muscle activity. Therefore, recognizing the signs of this syndrome is very important to prevent complications.

Prevention of Serotonin Syndrome depends on patients and doctors paying attention to the side effects of drugs that can cause this syndrome in order to combine drugs in treatment for safety and effectiveness.

Serotonin syndrome is a common and potentially life-threatening condition, but it can be prevented by paying attention to the side effects of medications that can cause it. Treatment of Serotonin syndrome usually depends on the severity of the condition.