PCT blood level is a specific parameter of severe bacterial inflammation, fungal infections, evidence of infection-related inflammation and multiple organ failure. PCT blood test is a specific marker for bacterial infection and sepsis.

Procalcitonin concentration evolution can be used as a parameter for differential diagnosis and early assessment of infection and sepsis. PCT determination should be performed and monitored daily. In special cases, determination should be performed at short intervals of 8 to 12 hours.