Swollen lymph nodes in the neck can be caused by many reasons, including metastatic cancer. Therefore, in some cases where lymph nodes are found in the neck but the diagnosis is unclear, a biopsy of the neck lymph nodes is performed to clarify the diagnosis.

After performing the lymph node procedure but there is still not enough data to diagnose the disease, the doctor needs to do more lymph node biopsy. This is an invasive procedure performed by a doctor in a hospital's sterile room.