Each of these chronic lymphocytic leukemia groups is further subdivided into several subtypes, which differ at the genetic level. This means that the disease manifests itself differently depending on the different genotypes. Two people with chronic B-cell lymphoma may still have different clinical presentations.

Chronic lymphocytic leukemia is a malignancy of the hematopoietic system that directly affects the lymphocytes in the body. Symptoms of chronic lymphocytic leukemia need to be detected early so that the patient can be diagnosed and treated promptly.