To achieve clinical implementation of AI, several steps need to be considered. Colling et al. presented a tentative roadmap for the routine use of AI in pathology practice. They highlighted key aspects of designing and implementing AI into daily practice. Steps related to design innovation, ethics, financing, development, validation, regulation, implementation, and workforce impact were closely examined. For pathology image analysis, various issues exist in the implementation of these steps, which will prevent AI from being implemented in clinical practice for gastrointestinal oncology.