Cholestatic liver disease can cause many dangerous complications that need to be treated properly to prevent serious complications that affect health and can even be life-threatening.

One of the major causes of cholestatic jaundice is choledochal cyst disease. This is a congenital cystic dilatation of the intra- or extrahepatic biliary system.

Jaundice is a yellow tint to the skin, often accompanied by yellowing of the mucous membranes and conjunctiva of the eyes. This is a characteristic manifestation of hepatobiliary diseases, of which the most common is jaundice due to biliary obstruction.

Biliary atresia in newborns is a disease that is very difficult to diagnose and can only be identified through screening. Currently, there are 2 screening methods for congenital biliary atresia proposed by medical experts: testing the concentration of direct bilirubin in the serum of jaundiced children and using stool cards for screening.

Congenital biliary atresia in children is a dangerous disease that needs to be treated early. Surgery is the optimal treatment method today. After surgery, the child needs careful care to avoid biliary tract infection and increased portal vein pressure.

Cholestasis in newborns is often caused by congenital biliary malformations or atresia. The prominent clinical symptom of the disease is generalized jaundice. The disease can be completely resolved without leaving serious sequelae if diagnosed and treated early.

Cholestasis of pregnancy occurs when the liver cannot properly excrete bile, causing severe itching in pregnant women. The itching occurs on the hands and feet, usually during the second trimester or during the third trimester of pregnancy.