Drug-induced liver damage is a rare but potentially fatal condition. The classes of drugs that cause liver damage can be prescription or non-prescription drugs, supplements, and herbal products.

AST (SGOT) and ALT (SGPT) are liver enzyme indicators that help reflect liver damage. Depending on the type of disease, these indicators will increase to a certain extent. If the cause of elevated liver enzymes is not corrected in time, these indicators may drop unexpectedly because there are no surviving liver cells.

Fatigue, indigestion, AST test result 255, reference value <40U/L and ALT test result 455 reference value <40U/L.

AST is an enzyme found primarily in the cells of the liver and kidneys, with smaller amounts also found in the heart and skeletal muscles. High levels of AST can indicate liver cell damage, but it can also be a sign of damage to other organs such as the heart or kidneys. Therefore, doctors often order AST tests along with other tests to evaluate liver function.

SGOT test is an important test in determining liver disease and monitoring disease progression. This test also helps determine the state of cell breakdown, especially due to liver, heart muscle, and skeletal muscle origin. When red blood cells are broken down, SGOT increases very high. What is the mechanism of this phenomenon?