What is Mekocetin?

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1. What is Mekocetin?

The main ingredient of Betamethasone 0.5mg. It is available in the form of a blue tablet. Betamethasone is a potent anti-inflammatory, anti-arthritic and anti-allergic drug used in the treatment of corticosteroid-responsive disorders. This is a glucocorticoid, having strong glucocorticoid activities and low mineralocorticoid activity.

2. What does Mekocetin do?

Thanks to its strong anti-inflammatory and immunosuppressive effects, Mekocetin is indicated for use in the following cases:
In respiratory tract infections: Can be used in acute pharyngitis, bronchitis, pneumonia, ear infections Between... In diseases caused by allergies: Allergic rhinitis, drug allergies, weather allergies... Arthritis, rheumatism, contact dermatitis... Cancer Collagen disease, skin disease eyes... Mekocetin's effects are very broad and are indicated flexibly depending on the individual case and the dose of betamethasone needed.

3. Contraindications of Mekocetin

Mekocetin drug should not be used in the following cases:
People who have ever had a hypersensitivity reaction to Betamethasone or other corticosteroids or to any component of the drug Mekocetin Do not use Betamethasone for people who are mentally ill, have stomach ulcers. and progressive duodenal bulb. Do not use in bacterial infections, viral infections and in systemic fungal infections. Use with caution in people with diabetes because it can cause hyperglycemia and difficulty controlling blood sugar levels.

4. How to use and dose Mekocetin

Mekocetin medicine is taken with water and should be taken in the morning around 8-9 am, after eating. The usual dose can be taken from 1-10 tablets / day.
Dosage is adjusted depending on the disease to be treated, the severity of the disease and the response of the patient. When there is improvement, gradually reduce the dose to the minimum maintenance level and stop the drug as soon as possible.
For acute diseases that usually do not exceed 5 days, chronic or drug-dependent diseases, use as directed by a doctor.

5. Side effects when taking Mekocetin

The possible side effects of Mekocetin, as with other corticosteroids, are usually related mainly to the dose and duration of treatment.
Water and electrolyte disorders: When taking corticosteroids, causing salt and water retention, there is a risk of congestive heart failure, decreased blood potassium, and increased blood pressure. On the musculoskeletal system: Causes muscle weakness, corticosteroid myopathy, loss of muscle mass, aggravation of myasthenia gravis, risk of osteoporosis, vertebral depression, aseptic necrosis of the femoral head and aseptic necrosis of the humerus head, pathological long bone fracture, ligament rupture. On the gastrointestinal tract: Causes peptic ulcer complications with gastric perforation or gastrointestinal bleeding, pancreatitis, abdominal distention, esophageal ulcer. Skin diseases: slow wound healing, thin skin, dilated capillaries; there are petechiae and the appearance of bruises on the skin; facial erythema; increased sweating; allergies such as atopic dermatitis, urticaria; neurovascular edema. May cause convulsions, increase intracranial pressure with papilledema (causes a type of brain pseudotumor) after treatment; dizzy; headache. Endocrine: menstrual disorders; Cushing's syndrome; secondary adrenal and pituitary loss of response, especially during times of stress; reduces carbohydrate tolerance; cause an increased need for insulin or the use of hypoglycemic agents in the treatment of diabetes. Eyes: Risk of subcapsular cataracts, glaucoma, bulging eyes. This risk is common in children, so it is important to be careful in children when using it for a long time. Psychiatric: causing a feeling of euphoria, a feeling of lightheadedness when taking drugs; manifestations of severe psychological impairment; erratic personality changes; insomnia . Other effects: Anaphylaxis or hypersensitivity reactions may occur, although these are very rare. Side effects of medications may not be the same for each person. When used correctly and for a short time, it is highly effective and has fewer side effects. You need to inform your doctor about any unwanted effects that you experience while taking the drug.

6. Notes when using Mekocetin

You should note the following when taking Mekocetin:
Must start from the lowest dose that can achieve control of the disease being treated; When taking a long-term or high dose, to stop the drug, the dose must be reduced and must be gradually reduced. Use the drug exactly as prescribed by the doctor, if you are taking it for a long time, do not suddenly stop using it. When systemic corticosteroids are used, extreme caution should be exercised in cases of congestive heart failure, new myocardial infarction, hypertension, epilepsy, progressive tuberculosis, hypothyroidism, glaucoma, and liver failure. , osteoporosis, kidney failure. Patients on corticosteroid therapy are more susceptible to infections due to their immunosuppressive effects. On the other hand, the symptoms of these infections may be masked by the potent anti-inflammatory drug, until late in the disease. This drug should be used with caution in pregnant women and for children. breastfeeding. Often these people are advised not to use it, only when absolutely necessary. Do not get certain vaccines during your corticosteroid treatment. Because it can cause adverse reactions affecting microorganisms, especially live attenuated vaccines. Other immunosuppressive therapies should not be used in corticosteroid therapy, especially at high doses because of the potential for neurological disturbances and loss of antibody response. But in patients who are being treated with corticosteroids as a hormone replacement therapy, such as Addison's disease, immunotherapy is okay. Long-term use of Betamethasone has a risk of causing cataracts, this is more common in children, glaucoma causes damage to the optic nerve. Should be very careful and need to check regularly for children. Patients taking corticosteroid doses cause a decrease in the immune response to pathogens, so it is important to avoid contact with infectious sources. This is especially important in children. Psychiatric disorders can also occur during corticosteroid therapy, which can aggravate psychological problems and predispose to psychosis.

7. Drug interactions

Drug interactions can occur when Mekocetin is used with other drugs. Therefore, caution should be exercised when using it with other drugs. Some possible drug interactions include:
Glucocorticoids increase the risk of hepatotoxicity when used with high doses of Paracetamol or long-term use. The drug increases or decreases the anticoagulant effect of anticoagulants such as coumarin, increasing the potential for arrhythmia or cardiac glycoside toxicity. Glucocorticoids will increase blood glucose levels, so in some cases it may be necessary to adjust the dose of the oral antidiabetic drug or the dose of insulin. Drugs such as Phenobarbitone, Phenytoin, Rifampicin, Ephedrine can reduce the therapeutic effect of corticosteroids. Exogenous estrogens can enhance the therapeutic effects and increase the toxicity of glucocorticoids. When combined with non-steroidal anti-inflammatory drugs or alcohol may increase the risk of developing gastrointestinal or severe ulcers. In addition, patients should note that they should be stored at a temperature below 25 degrees Celsius in a sealed package. Protect from light and do not keep the medicine in the freezer. Keep out of reach of children.
The main use of Mekocetin is anti-inflammatory, immunosuppressive. It can be highly effective in treating disease, but it needs to be used with caution.

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