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Kuplevotin 25mg is a drug indicated for the treatment of peptic ulcers. In addition, the drug is also effective in the treatment of chronic schizophrenia. To ensure effective use, patients need to strictly follow the instructions of the doctor, professional pharmacist.
1. What is Kuplevotin 25mg?
Kuplevotin medicine 25mg has the main ingredient Levosulpiride 25mg. The drug is available in the form of film-coated tablets.
2. Indications and contraindications of Kuplevotin 25mg
2.1. Indications Kuplevotin 25mg is indicated in the following cases:
Treatment of disorders in the body form. Treatment of chronic schizophrenia comes along with negative symptoms. Treatment of some digestive tract diseases such as gastroesophageal reflux disease, irritable bowel syndrome, symptoms of persistent stomach pain, flatulence, diarrhea, constipation. 2.2. Contraindication of Kuplevotin 25mg Kuplevotin drug 25mg is contraindicated in the following cases:
Patients with hypersensitivity to any ingredient in the drug Kuplevotin 25mg Acute porphyria metabolic disorders Adrenal myeloma Patients in in a depressed central nervous state Patient is in a coma Alcohol poisoning or is taking other neuroleptic drugs.
3. How to use and dose Kuplevotin 25mg
How to use: Patients need to take Kuplevotin 25mg orally and should drink it with filtered water.
Specific dosage is as follows:
Usual dose when treating gastrointestinal diseases:
Use 75mg/day and divide into 3 equal doses Usual dose when treating schizophrenia:
Take 200 – 300mg/day and divided into 3 equal doses Note: Reduce dose for children 14-18 years old. Absolutely do not use Kuplevotin 25mg for children under 14 years old.
In addition, it is necessary to adjust the dose of Kuplevotin 25mg in patients with impaired renal function, specifically as follows:
Creatinine clearance 30-60ml/min: Use 2/3 of the usual dose Clearance Creatinine clearance 10 - 30ml/min: Use 1/2 dose of the usual dose Creatinine clearance less than 10ml/min: Use 1/3 of the usual dose
4. Notes when using Kuplevotin 25mg
In the process of using Kuplevotin 25mg, patients should pay attention to the following issues:
If using Kuplevotin 25mg for patients with kidney failure, it is necessary to adjust the dose and closely monitor complications, as well as effects on the function of this organ. Epilepsy patients using Kuplevotin 25mg drug have a lower possibility of convulsions. The elderly are prone to drowsiness and orthostatic hypotension. Therefore, you need to be very careful with these two objects. The use of alcohol and alcoholic beverages and stimulants with Kuplevotin may increase symptoms of drowsiness and loss of concentration. In addition, during the time of taking Kuplevotin 25mg, if the patient has a high fever of unknown cause, it is necessary to stop taking Kuplevotin 25mg immediately to rule out the possibility of neuroleptic malignant syndrome.
5. Side effects when using Kuplevotin 25mg
During the use of Kuplevotin 25mg, the patient may experience some of the following side effects:
Common side effects:
Nervous system: The patient may feel drowsy or insomnia Endocrine: increase lactation, amenorrhea, menstrual disorders, hyperprolactinemia,... Uncommon side effects:
Nervous system: Parkinson's syndrome, extrapyramidal syndrome and overstimulation. Cardiovascular: Prolonged QT interval Rare side effects:
Endocrine: Abnormal breast enlargement in men Nervous system: malignant high fever syndrome, tardive dyskinesia,... Blood pressure: Arrhythmia heart rate, bradycardia, orthostatic hypotension,...
6. Notes when using Kuplevotin 25mg
Pregnant women: Kuplevotin can cross the placenta and cause negative effects on the fetal nerves. Therefore, Kuplevotin 25mg is not recommended for pregnant women, especially during the first trimester. Lactation: Kuplevotin can be distributed through breast milk, thereby affecting the health of the baby. Therefore, to ensure safety, the mother should stop breastfeeding or ask the doctor to prescribe a more appropriate medication. Using drugs for driving and operating machinery: Using Kuplevotin medicine can increase the feeling of drowsiness, dizziness, nervous disorders. Therefore, caution should be exercised if people drive and operate machinery while using Kuplevotin 25mg
7. Drug interactions Kuplevotin 25mg
Antacids containing aluminum/magnesium hydroxide: These drugs have the ability to reduce the absorption of Levosulpiride, making the effect of the drug impaired. Therefore, patients should take Kuplevotin 2 hours after taking it. acid resistance. Levodopa: Levodopa-containing drugs and neuroleptics are contraindicated with Levodopa because of their competitive antagonism. Antihypertensives: Concomitant use may increase the risk of orthostatic hypotension. Therefore, a dose adjustment is required if the combination is intended. Lithium: Concomitant use increases the blockade of Levosulpiride with dopaminergic D2 receptors in the brain. Therefore, there is the possibility of extrapyramidal disorders. Other CNS depressants: May increase the CNS depressant effect. Alcohol: May increase the sedative effect of Levosulpiride. In summary, Kuplevotin 25mg is a drug for the treatment of peptic ulcers. In addition, the drug is also effective in the treatment of chronic schizophrenia. To ensure effective use, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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