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Doxylamine Pyridoxine is a combination form of an antihistamine group, which is circulated and used with the effect of preventing morning sickness in pregnancy. So, what are the effects of Doxylamine Pyridoxine for pregnant women? Find out more about this drug in the following article.
1. What is Doxylamine Pyridoxine?
Doxylamine Pyridoxine is a collection of drugs, or generic names for prescription drugs intended to treat nausea and vomiting in women during pregnancy.
Two pharmaceutical brands have registered to release Doxylamine Pyridoxine, Diclegis and Bonjesta, with a 10mg delayed release tablet called Diclegis and a 20mg extended release tablet called Bonjesta.
Doxylamine Pyridoxine drug is composed of 2 main active ingredients as their names are Doxylamine and Pyridoxine and other excipients. While Doxylamine helps antihistamine and Pyridoxine helps provide more B vitamins (specifically B6) for the mother's body. These two drugs are combined to reduce the symptoms of vomiting and nausea and morning sickness in women during pregnancy.
2. What is the effect of Doxylamine Pyridoxine?
Nausea and vomiting are very common during pregnancy, most commonly between 6 and 12 weeks. Usually these symptoms go away on their own, but some women experience severe nausea, also known as severe morning sickness. Manifestations in body weight loss, electrolyte imbalance, malnutrition,...
Doxylamine and Pyrudoxine (Vitamin B6) which are approved by the US Food and Drug Administration (FDA) and labeled as safe for pregnant women's health to use to reduce spasms and ease symptoms of vomiting and morning sickness in this subject. Specifically, with the two brands introduced above, we have two drug lines as follows:
Diclegis: Drugs in the form of tablets, slow release. Composed of 10 mg of doxylamine and 10 mg of slow-acting pyridoxine
Bonjesta: The drug comes as a tablet, combined release. The drug includes an immediate-release coating, consisting of 10 mg of doxylamine and 10 mg of pyridoxine; enteric coating consisting of 10 mg of doxylamine and 10 mg of pyridoxine.
3. Usage of Doxylamine Pyridoxine
3.1. How to use Doxylamine Pyridoxine For Doxylamine Pyridoxine, pregnant women use it orally by swallowing whole tablets with cooled boiled water. Because the side effect of the drug is easy to cause drowsiness, women can use the drug before going to bed so that the symptoms of drowsiness do not affect physical activity.
3.2. Dosage of Doxylamine Pyridoxine Diclegis: Pregnant women need to take 2 slow-release tablets daily before going to bed.
Where symptoms are not adequately controlled, consider increasing the dose to 4 tablets a day (1 tablet in the morning, 1 tablet in the afternoon; 2 tablets at bedtime).
Bonjesta: Pregnant women take 1 pill before going to bed.
If this dose has completely controlled the symptoms the next day, you can continue taking 1 tablet / day just before going to bed.
Where symptoms persist, pregnant women may consider increasing the daily dose to 1 tablet in the morning and 1 tablet at bedtime.
3.3. Treatment in case of forgetting, overdosing Missed dose:
Pregnant women should consult a doctor in case of missed dose. The health of the baby is very important. Remember, never take a double dose as prescribed.
Overdose:
There have been no reports of overdose related to Doxylamine Pyridoxine
3.4. Contraindicated Doxylamine Pyridoxine Contraindicated in pregnant women who are allergic or hypersensitive to Doxylamine, Pyridoxine or any component of the drug
Contraindicated in pregnant women using concomitantly with MAO inhibitors
4. Notes when using Doxylamine Pyridoxine drug
4.1 Side effects of Doxylamine Pyridoxine When using Doxylamine Pyridoxine, pregnant women may experience common side effects such as:
Symptoms such as drowsiness, dizziness, stomach pain, diarrhea, constipation, ... Possible reactions such as palpitations, tachycardia, shortness of breath, difficulty urinating,... 4.2 Doxylamine Pyridoxine Drug Interactions When using Doxylamine Pyridoxine, special care should be taken with other drugs. concurrent use with this product. Doxylamine Pyridoxine has a particularly severe reaction to more than 10 drugs and a moderate response to 156 drugs.
When you want to use medicinal products in parallel, pregnant women should listen to the advice of doctors and advice of reputable medical facilities.
4.3 Store Doxylamine Pyridoxine Doxylamine Pyridoxine Store Doxylamine Pyridoxine in a cool, dry place, do not let sunlight shine on the product.
The appropriate storage temperature for Doxylamine Pyridoxine is between 20 degrees and 28 degrees Celsius.
Store the tablets in the manufacturer's packaging, do not open them first.
Pregnant women are not allowed to take the medicine when the expiry date printed on the package has expired, the pill is discolored or changed in taste.
Doxylamine Pyridoxine is a prescription drug, so when there is a need to buy, it is necessary to have a doctor prescribe it and designate it for use. Pregnant women should adhere to the use of the drug according to the instructions for use listed on the Doxylamine Pyridoxine leaflet or the doctor's prescription.
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