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Doncef 500mg drug belongs to the group of antibiotics with the main ingredient being Cefradine. Doncef 500mg is used in the treatment of infections of the respiratory tract, urinary tract, skin and soft tissue structures, prostate gland, other serious and chronic infections, as well as the prophylaxis of infections during and after surgery.
1. What is Doncef 500mg?
Doncef 500mg drug belongs to the group of systemic antibiotics, the main ingredient is Cefradine 500mg. Cefradin belongs to the group of first-generation semi-synthetic cephalosporins, which have bactericidal effects by inhibiting mucopeptides synthesized on bacterial cell walls.
Doncef 500mg drug is made in the form of hard capsules, indicated for use in the treatment of specific infections as follows:
Infections of the skin and subcutaneous soft tissue structures. Respiratory tract infections (including lobar pneumonia). Prophylaxis of infection in surgery and other surgical treatment. Urinary tract infections. Bacterial infections cause prostatitis. Other chronic and serious infections.
2. Dosage and how to use Doncef 500mg
Doncef 500mg drug is taken orally, taken with a sufficient amount of water, can be taken with or without meals. The specific dosage of Doncef 500mg is as follows:
Adults: Take a dose of 250mg - 500mg/every 6 hours or 500mg - 1g/every 12 hours. The maximum dose is 4g/day. Patients with renal impairment: Reduce dose in patients with severe renal impairment and depending on creatinine clearance, namely 500 mg/every 6 hours (creatinine clearance above 20 ml/min), 250 mg/every 6 hours (creatinine clearance above 20 ml/min), 250 mg/every 6 hours (clearance). creatinine 5 – 20 ml/min) and 250 mg/every 12 hours (creatinine clearance from less than 5 ml/min). Depending on your condition and medical condition, your doctor will prescribe the appropriate dose of Doncef 500mg. Therefore, to ensure safety, patients should consult with their doctor or pharmacist to know the dose corresponding to disease progression.
Doncef 500mg overdose may experience symptoms such as epigastric pain, nausea, vomiting, diarrhea and bloody urine. Then, depending on the symptoms, there will be appropriate treatment measures such as infusion of electrolytes, using activated charcoal to reduce drug absorption in the gastrointestinal tract, hemodialysis and peritoneal dialysis to reduce the concentration of cefradine in the blood. blood.
3. Side effects of the drug Doncef 500mg
Doncef 500mg medicine can cause some unwanted side effects in moderate and mild such as urticaria, rash, diarrhea, nausea, vomiting, headache. These symptoms disappear when the patient stops taking the drug.
After taking Doncef 500mg, if there are any abnormal symptoms, the patient should immediately contact a doctor or medical facility for advice on how to handle.
4. Some notes when using Doncef 500mg
Do not use Doncef 500mg in people with hypersensitivity to the ingredients of the drug. People with a history of allergy to Cephalosporin antibiotics, penicillin should be cautious when taking Doncef 500mg and before taking any systemic antibiotic, please inform your doctor in advance to prevent risks. People with kidney failure need to adjust the dose of Doncef 500mg as above and in the process of taking the drug, it is necessary to monitor the color composition, kidney function, especially in the case of high doses or high doses for a long time. Pregnant and lactating women should consider taking Doncef 500mg because the antibiotic component Cefradin can be transmitted through the placenta and breast milk, affecting the fetus in the womb and the nursing infant. Doncef 500mg may interact with Probenecid drugs and increase Cefradin concentrations when these two drugs are taken together. Therefore, in order to limit changes due to drug interactions, patients should inform their doctors about all medications they have been taking, including prescription and non-prescription drugs, dietary supplements, herbs, and supplements. medicine. Doncef 500mg drug is an antibiotic, effective in the treatment of respiratory tract infections, urinary tract infections, skin and soft tissue infections, bacterial prostatitis. In addition, the drug is also used in the prevention of infections during surgery or other serious and chronic infections.
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