This is an automatically translated article.
The drug Chalme has two main ingredients: Aluminum Hydroxide and Magnesium Hydroxide antacids. The drug is indicated for the treatment of gastric diseases. To ensure effective treatment and avoid side effects, patients need to take the medicine exactly as directed.
1. What is Chalme?
The drug Chalme has two main ingredients: Aluminum Hydroxide and Magnesium Hydroxide antacids. Prepared in the form of a suspension packing the drug with a content of 15 grams. Chalme is a product of Dat Vi Phu Pharmaceutical Co., Ltd.
Chalme medicine contains two ingredients that are strong antacids, so it works to treat diseases such as stomach ulcers, reduce symptoms of flatulence, indigestion, and stomach dysfunction. The drug is absorbed from the intestine and excreted in the feces.
2. What does Chalme do? Chalme's mechanism of action
Aluminum Hydroxide: Dissolves slowly in gastric juice and reacts with Hydrochloric Acid to form water and aluminum chloride. In patients with normal renal function, the amount of aluminum chloride formed is absorbed and excreted by the kidneys about 17 to 30%. In the small intestine, aluminum chloride continues to be rapidly converted into insoluble aluminum salts, so it is difficult for the body to absorb. Phosphate in the intestine also combines with aluminum to form insoluble aluminum phosphate, which is not absorbed into the intestine and continues to be excreted in the feces.
In patients with normal renal function, if the amount of Phosphate in the body is within the limit, the use of drugs containing aluminum Hydroxyd will reduce the absorption of Phosphate, and may also cause hypophosphatemia and hypophosphatemia. urine, resulting in increased calcium absorption.
Magnesium hydroxide: Although magnesium hydroxide is classified by researchers as an antacid with no systemic effect, in fact, 5 to 10% is absorbed into the body. Magnesium is metabolized and eliminated by the kidneys very rapidly. In normal subjects, absorption does not cause systemic alkalosis, but urine is alkaline.
Thuốc Chalme được chỉ định dùng trong điều trị một số bệnh lý dạ dày
3. Contraindications of the drug Chalme
Do not use the drug for patients who are allergic to any of the ingredients of Chalme. Children especially those with kidney failure and dehydration Adults with severe kidney failure Patients with hypophosphatemia, alkalosis Patients with high levels of magnesium in the blood Be careful when taking Chalme
In patients with diabetes It should be noted, because in the composition of Chalme contains Saccharin. Use with caution in patients with mild and moderate renal impairment. Patients on chronic dialysis (risk of encephalopathy from aluminum accumulation). Periodic monitoring of phosphate levels during long-term treatment. The drug can be used for pregnant and lactating women, but high doses and prolonged use should be avoided. Can be used for pregnant women but should be used in standard doses, avoid prolonged high doses
4. Side effects when taking Chalme
Side effects that you should report to your doctor as soon as possible:
Allergic reactions such as skin rash, itching or hives, swelling of the face, lips or tongue Bone or joint pain Confusion or irritability Pain Head Loss of appetite Really nausea or vomiting Unusual weakness or fatigue
5. Chalme drug interactions
Avoid taking Chalme with Tetracycline antibiotics, anti-muscarinic drugs, Diazepam, Cimetidine, Digoxin, iron-containing preparations, INH, Phenothiazine group drugs, fat-soluble vitamins.
Tell your doctor and pharmacist what prescription and nonprescription medicines you are taking, especially aspirin, cinoxacin (Cinobac), ciprofloxacin (Cipro), digoxin (Lanoxin), diazepam (Valium), enoxacin ( Penetrex), ferrous sulfate (iron), fluconazole (Diflucan), indomethacin, isoniazid (INH), itraconazole (Sporanox), ketoconazole (Nizoral), levofloxacin (Levaquin), lomefloxacin (Maxaquin), nalidixic acid (NegGram), norfloxacin (Noroxin). ), ofloxacin (sparfloxacin), tetracycline (Achromycin, Sumycin) and vitamins. If your doctor tells you to take antacids while taking these drugs, do not take them within 2 hours of taking the antacid.
The above list may not be descriptive of all possible drug interactions. Therefore, provide your doctor with a list of all the medications, herbs, over-the-counter medications or supplements you take. Also, let them know if you smoke, drink or use drugs.
Người bệnh nên dùng thuốc Chalme theo chỉ định của bác sĩ để tránh tương tác thuốc
6. How to use Chalme
6.1. How to use Chalme medicine Chalme drug is taken orally. You need to read the instructions carefully before using . After taking this medicine, drink a full glass of water. Antacids are usually taken after meals and at bedtime, or as directed by your doctor. You should stay in an upright position for 1 to 2 hours after taking this medicine. Take your medicine regularly and do not take more than directed.
6.2. Dosage of Chalme To antacid (the cause of indigestion, heartburn, stomach disorders): Depending on the condition of each patient, the dose of Chalme needed to neutralize stomach acid will change. difference. Usually will depend on the amount of gastric acid secreted and the buffering capacity of each individual preparation.
Mixture of antacids containing magnesium compounds with aluminum has the outstanding advantage of overcoming the constipation of aluminum hydroxide thanks to the laxative properties of magnesium hydroxide.
According to the recommended maximum dose for the treatment of symptoms of indigestion, digestive disorders should not be used for more than 14 days, unless it is prescribed by a doctor or under the supervision of a physician.
Used to treat peptic ulcer disease: In order for the drug to maximize the antacid effect at the most optimal time, you should take antacids from 1 to 3 hours after the main meal and right before. at bedtime to prolong the neutralizing effect of gastric juice. Additional doses may be taken for pain relief between the main prescribed doses. For the treatment of peptic ulcers, the dosage of antacids is used as directed by your doctor, and it is often not the same for each person.
It is difficult to do routine testing and there is no relationship between the relief of heartburn, indigestion or stomach upset and the ulcer has healed, so it is important to keep taking antacids for at least 4 to 6 weeks after when symptoms are gone.
Specific oral dosage
In the treatment of peptic ulcer disease:
Children: usual dose 5 to 15 grams of suspension, every 3 to 6 hours or 1 to 3 hours after meals eat main meals and just before going to bed; Adults: usual dose 15 to 45 grams of suspension, every 3 to 6 hours or 1 to 3 hours after meals, main meals and just before bedtime Prevention of gastrointestinal bleeding:
Children children: 2 to 5 grams of suspension/dose, 1 to 2 hours apart; Older children: 5 to 15 grams of suspension/dose, 1 to 2 hours apart; Adults: 30 to 60 grams of suspension, 1 hour apart; It is necessary to adjust the dose of Chalme to maintain gastric pH > 5.
For antacid (relieves symptoms of heartburn, indigestion, stomach disorders):
Adults take 30g of suspension, at 1 to 3 hours. hours after meals and at bedtime. Note: The above dosage is for reference only. The specific dose of the drug depends on the patient's condition and the progression of the disease. To get the right dose, you need to consult your doctor or healthcare professional.
Patients should be careful not to exceed the prescribed dose. Taking more of them won't improve your symptoms, they can cause poisoning or serious side effects. If Chalme overdose and side effects appear, you should go to a medical facility for examination and monitoring.
The drug Chalme has two main ingredients: Aluminum Hydroxide and Magnesium Hydroxide antacids. The drug is indicated for the treatment of gastric diseases. To ensure the effectiveness of treatment and avoid side effects, patients need to carefully read the instructions and consult a doctor or pharmacist.
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