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Prazopro medicine is made in the form of capsules, used in the treatment of a number of diseases in the stomach, esophagus and duodenum. So what is Prazopro?
1. Uses of Prazopro
Prazopro medicine has the ingredient Esomeprazole (Esomeprazole magnesium granules are coated in the intestine). The drug is prepared in the form of capsules, with strength forms including Prazopro 20mg, Prazopro 40mg. Esomeprazole is the S-isomer of omeprazole. This is a specific inhibitor of proton pump (H + K +) ATPase of gastric parietal cells, capable of preventing and reducing gastric acid secretion.
Prazopro is indicated in the following cases:
Treatment of benign gastric and duodenal ulcers; Prevention and treatment of gastric and duodenal ulcers caused by taking non-steroidal anti-inflammatory drugs (NSAIDs); Treatment of Zollinger-Ellison syndrome; Treatment of gastroesophageal reflux disease - esophagitis: erosive, ulcerative or narrow esophagitis (determined by endoscopy). The use of Prazopro is contraindicated in people who are sensitive to one of the ingredients in the drug and children under 18 years of age.
2. Usage and dosage of Prazopro
Prazopro is used orally. Patients should take the medicine as prescribed by the doctor, about 1 hour before meals.
Reference dosage of Prazopro:
Gastric ulcer - duodenal ulcer due to Helicobacter Pylori infection: Esomeprazole 40mg 1 time/day in combination with Clarithromycin 500mg + Amoxicillin 1g x 2 times/day. Drink regimen for 10 days; Zollinger-Ellison syndrome: Depending on the patient and the degree of gastric acid secretion, the dose will be higher than in other cases, it can be taken once or divided into several times. In case the tumor is not removed, it is necessary to take long-term drugs; Treatment of gastroesophageal reflux - oesophagitis with esophagitis: Prazopro 40mg dose 1 time / day for 4-8 weeks. May be increased by 4 to 8 weeks if symptoms persist or inflammation persists on endoscopic examination. Overdose: There have been no reports of an overdose of Prazopro. When taking an overdose, only symptomatic treatment is available because there is currently no specific treatment.
Missed dose: Take the medicine as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose as scheduled.
3. Side effects of the drug Prazopro
When using Prazopro, patients may experience some unwanted side effects:
Common: Abdominal pain, headache, constipation, nausea, vomiting, diarrhea, bloating; Rare: Thrombocytopenia, agitation, confusion, angioedema fever, depression, taste disturbances. When experiencing side effects while using Prazopro, patients should notify their doctor immediately.
4. Be careful when using Prazopro
Before and while using Prazopro, patients should be aware:
Esomeprazol (a component of Prazopro) can mask symptoms, delay the diagnosis process in patients with malignant lesions in the stomach; Prazopro should be used with caution in people with liver disease, pregnant or lactating women (consult your doctor); Esomeprazole should be used with caution for a long time because this ingredient can cause atrophic gastritis; For reflux disease, it is recommended to combine the use of Prazopro with a reasonable and scientific diet.
5. Prazopro . drug interactions
Some drug interactions of Prazopro include:
The decrease in gastric acid level during treatment with Esomeprazole may increase/decrease the absorption of other drugs (if the absorption mechanism of these drugs is affected by the degree of toxicity). stomach acid). Specifically, the absorption of itraconazole and ketoconazole may be reduced when patients are treated with Esomeprazole; Esomeprazole inhibits CYP2C19, the major enzyme that metabolizes Esomeprazole. Therefore, when Esomeprazole is used together with drugs metabolised by CYP2C19 such as citalopram or diazepam, plasma concentrations of these drugs may be increased and dose reduction may be required; Concomitant use of Esomeprazole with amoxicillin and clarithromycin increases blood levels of Esomeprazole and 14 hydroxy clarithromycin. To ensure the safety and effectiveness of the use of Prazopro, patients should inform their doctor about the drugs they are taking, the diseases they are suffering from. During the course of taking the drug, the patient should strictly follow all the instructions of the doctor.
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