What is Bactamox 1g?

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1. Uses of Bactamox 1g

What is Bactamox 1g? Bactamox belongs to the group of antibiotics, with the main ingredients including 875mg Amoxicillin and 125mg Sulbactam. In particular, Amoxicillin is a semi-synthetic beta-lactam antibiotic with a broad bactericidal spectrum against many gram-negative and gram-positive bacteria (due to its ability to inhibit bacterial cell wall synthesis). However, Amoxicillin is easily destroyed by beta-lactamases, so it has no effect on bacteria that produce these enzymes. Sulbactam is a competitive, irreversible, beta-lactamase inhibitor. The presence of Sulbactam in the drug component increases the effect, expands the antibacterial spectrum of Amoxicillin against beta-lactamase-producing strains.
Indications for use of Bactamox 1g: Treatment of infections caused by sensitive bacteria, including:
Ear - nose - throat infections: otitis media, tonsillitis, sinusitis; Lower respiratory tract infections: Bronchopneumonia, acute and chronic bronchitis; Genitourinary tract infections: urethritis, cystitis, pyelonephritis, female genital tract infections; Skin and soft tissue infections: Wound infections, boils, abscesses; Bone and joint infections; Dental infections: Alveolar abscess; Other infections: Obstetric bacteremia, intra-abdominal infection, infection due to abortion. Contraindications to the use of Bactamox 1g:
People who are sensitive to drug components or antibiotics of the Cephalosporin, Penicillin group; People with a history of gastrointestinal disease, especially Crohn's disease, antibiotic-associated colitis or ulcerative colitis; People with a history of jaundice or liver dysfunction; People with renal failure with creatinine clearance ClCl less than 30ml/min; Children under 12 years old.

2. Usage and dosage of Bactamox 1g

How to use: Orally, before or after meals.
Dosage: The drug is used in case of severe infection, for people 12 years and older is 1 tablet x 2 times/day.
Overdose: Patients should not take Bactamox more than the prescribed dose, as it can cause poisoning or lead to serious side effects. If you suspect that you or someone else has overdosed, you should immediately go to the hospital for examination and treatment. Interventions may include induction of vomiting and gastric lavage in case of recent drug overdose. There is currently no specific antidote. Amoxicillin and Sulbactam can be removed from the body by hemodialysis.
Missed dose: If you forget to take a dose of Bactamox, the patient should take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time.

3. Side effects of Bactamox 1g

When using Bactamox, patients may experience some side effects such as:
Common: Diarrhea, skin itching, rash; Uncommon: Nausea, vomiting, rash, eosinophilia, increased transaminases, hepatitis and cholestatic jaundice; Rare: Anaphylaxis, thrombocytopenia, leukopenia, Quincke's edema, hemolytic anemia, pseudomembranous colitis, erythema multiforme, Stevens-Johnson syndrome, exfoliative dermatitis, epidermal necrolysis due to poisoning, interstitial nephritis. When experiencing side effects of the drug, patients should stop taking Bactamox and immediately notify the doctor or go to the nearest hospital for timely intervention.

4. Be careful when using Bactamox 1g

Some notes users need to remember when using Bactamox 1g:
Signs and symptoms of cholestatic jaundice are rare when using the drug, but can progress to severe. However, these symptoms are usually reversible, disappearing after about 6 weeks of stopping treatment; There have been cases of severe hypersensitivity reactions, sometimes leading to death in the form of anaphylaxis; There have been cases of patients taking Amoxicillin develop erythema associated with lymphadenopathy (infective mononucleosis). Therefore, Bactamox should be avoided if the patient is suspected of having infectious mononucleosis; Prolonged use of Bactamox 1g can sometimes lead to the development of resistant bacteria; Avoid using Bactamox in pregnant women, especially during the first 3 months of pregnancy (unless otherwise authorized by your doctor); Because Amoxicillin and Sulbactam are excreted in human milk, caution should be exercised when administering the drug to nursing mothers. Before taking the drug, a woman who is breast-feeding should consult a doctor.

5. Bactamox drug interactions 1g

Some drug interactions of Bactamox include:
Bactamox medicine can prolong bleeding and clotting time; Bactamox can reduce the effectiveness of oral contraceptives, so doctors need to warn patients about this risk; Probenecid reduces the excretion of Bactamox drug through the renal tubules, thus increasing the drug concentration in the blood; Nifedipine increases the absorption of the Amoxicillin component of the drug; Components Amoxicillin reduces the excretion of Methotrexate and increases toxicity on the gastrointestinal tract, hematopoietic system; Concomitant use of Bactamox with Allopurinol increases the risk of allergic skin reactions; The drugs Macrolid, Sulfamide, Chloramphenicol and Tetracycline can interfere with the bactericidal effect of Amoxicillin. To ensure the highest effectiveness when using Bactamox 1g, patients should inform their doctor about their medical history and any medications they are taking. At the same time, if you experience any side effects, the patient should inform the doctor immediately.
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